Results 91 to 100 of about 377,166 (313)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Lattice-Based Group Signatures with Logarithmic Signature Size [PDF]
, 2013 Group signatures are cryptographic primitives where users can anonymously sign messages in the name of a population they belong to. Gordon {\em et al.} (Asiacrypt 2010) suggested the first realization of group signatures based on lattice assumptions in the random oracle model.
Laguillaumie, Fabien +3 more
openaire +3 more sources
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
, 2012 The bottlenose dolphin uses vocal learning to develop its own unique acoustic signal. This signal encodes the identity of the signaller, and is known as the animal’s signature whistle.
King, Stephanie Laura
core
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Geographic and species variation in bottlenose dolphin (Tursiops spp.) signature whistle types
, 2011 Geographic variation in the whistle vocalisations of dolphins has previously been reported. However, most studies have focused on the whole whistle repertoire, with little attempt to classify sounds into biologically relevant categories.
Gridley, Teresa
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Cryptanalysis of an efficient group signature schemen
Tongxin xuebao, 2007 The security flaws of the group signature proposed by Zhang Jianhong and etc.was analyzed.It pointed out that the group signature was not untraceable for the revocation center could not open a valid group signature.A coalition attack that the manager and
LU Rong-bo1, XUAN Heng-nong3, HE Da-ke2
doaj
Verifiable Encryption and Applications to Group Signatures and Signature Sharing
BRICS Report Series, 1998 We generalise and improve the security and efficiency of the verifiable encryption scheme of Asokan et al., such that it can rely on more general assumptions, and can be proven secure without relying on random oracles. We show a new application of verifiable encryption to group signatures with separability, these schemes do not need special purpose ...
Jan Camenisch, Ivan Damgård
openaire +3 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source