Results 131 to 140 of about 377,166 (313)
A Non-repudiable Multi-Proxy Multi-Signature Scheme
, 2012 [[abstract]]In this paper, we shall propose a threshold multi-proxy multi-signature scheme with shared verification. In the scheme allows the group of original signers to delegate the signing capability to the designated group of proxy signers ...
黃明祥;Hwang, Min-Shiang
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Cryptanalysis of A New Multi-Proxy Multi-Signature Scheme
, 2009 [[abstract]]Recently, Hwang and Chen [5] proposed a variation of proxy signature scheme called the multi-proxy multi-signature scheme. In their scheme, an authorized group of proxy signers is allowed to sign message on behalf of a group of original ...
孫宏民;謝濱燦;林宸堂
core
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Breaking and Building of Group Inside Signature [PDF]
, 2009 Group Inside Signature (GIS) is a signature scheme that allows the signer to designate his signature to be verified by a group of people, so that members other than the designated group cannot verify the signature generated by him.
C. Pandu Rangan +3 more
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Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Attacks on Threshold Signature Schemes with Traceable Signers
, 2012 [[abstract]]In 1998, Wang et al. proposed two new (t,n)-threshold signature schemes with traceable signers that can withstand conspiracy attacks without attaching a secret number.
Tseng, Yuh-Min; Jan, J. K.
core
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
A Threshold Signature Scheme Withstanding the Conspiracy Attack
, 2012 [[abstract]]A threshold signature, first proposed by Desmedt and Frankel, allows or more members of the group cooperate to generate a signature on behalf of the group while providing the anonymity of the signers.
Jan, Jinn-Ke; Tseng, Yuh-Min; Chien, Hung-Yu
core