Results 181 to 190 of about 377,166 (313)

Construction of an efferocytosis related signature to predict the prognosis of pancreatic ductal adenocarcinoma. [PDF]

Discov Oncol
Li J, Du Z, Liu X, Pan T, Zheng Y, He Y.
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Predicting prognosis and drug sensitivity in patients with hepatocellular carcinoma using an lncRNA signature associated with cuproptosis. [PDF]

BMC Cancer
Li Y, Lv S, Wang Y.
europepmc   +1 more source

An Efficient Group-oriented (t,n) Threshold Signature Scheme with Message Linkage

, 2012
[[abstract]]In 1999, Chen (1999) proposed several signature schemes in his graduate thesis. One is a group-oriented (t,n) threshold signature scheme in which the (t,n) threshold signature is based on an RSA scheme.
Perng, Chi-Yow; Jan, Jinn-Ke; Tseng, Yuh-Min
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

A Propionate Metabolism-Based Gene Signature Reveals Immunogenomic and Transcriptomic Determinants of Prognosis in Glioblastoma Through Multiomics Integration. [PDF]

Hum Mutat
Li M, Liu J, Liu Z, Liu X, Lun P.
europepmc   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Comprehensive analysis of mutational signatures and corresponding driver genes in cervical cancer from Xinjiang. [PDF]

Biochem Biophys Rep
Chen C, Zhao W, Guo M, Wang W, Ma J, Niyazi M, Zhu K.   +6 more
europepmc   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Development and Validation of an m6A-Derived Prognostic Signature in Lung Adenocarcinoma. [PDF]

J Cancer
Shao Z, Situ Y, Lai B, Xu Y, Chen J, Deng L, Xu Q, Liang M, Liang Z, Xie Z.   +9 more
europepmc   +1 more source