Results 141 to 150 of about 9,037,671 (282)

How group structure impacts the numbers at risk for coronary artery disease: polygenic risk scores and non-genetic risk factors in the UK Biobank cohort

, 2023
Zhao J, O’Hagan A, Salter-Townshend M.
europepmc   +1 more source

Habitat and social factors shape individual decisions and emergent group structure during baboon collective movement. [PDF]

Elife, 2017
Strandburg-Peshkin A, Farine DR, Crofoot MC, Couzin ID.   +3 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Correction: Including population and environmental dynamic heterogeneities in continuum models of collective behaviour with applications to locust foraging and group structure. [PDF]

PLoS Comput Biol
PLOS Computational Biology Staff.
europepmc   +1 more source

Multivariate sparse group lasso for the multivariate multiple linear regression with an arbitrary group structure. [PDF]

Biometrics, 2015
Li Y, Nan B, Zhu J.
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Group Structure as a Foundation for Entropies. [PDF]

Entropy (Basel)
Jensen HJ, Tempesta P.
europepmc   +1 more source

Modeling gene-covariate interactions in sparse regression with group structure for genome-wide association studies. [PDF]

Stat Appl Genet Mol Biol, 2015
Li Y, O'Connor GT, Dupuis J, Kolaczyk E.
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Including population and environmental dynamic heterogeneities in continuum models of collective behaviour with applications to locust foraging and group structure. [PDF]

PLoS Comput Biol
Georgiou F, Buhl C, Green JEF, Lamichhane B, Thamwattana N.   +4 more
europepmc   +1 more source