Results 111 to 120 of about 324,883 (267)

Structure and representation theory for the double group of the four-dimensional cubic group

open access: yes, 2001
Hypercubic groups in any dimension are defined and their conjugate classifications and representation theories are derived. Double group and spinor representation are introduced. A detailed calculation is carried out on the structures of four-dimensional
Jian Dai   +3 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

On the K-Theory of Crystallographic Groups [PDF]

open access: yesTransactions of the American Mathematical Society, 1995
For any crystallographic group Γ \Gamma
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Radion-Higgs mixing in 2HDMs

open access: yesJournal of High Energy Physics, 2018
We study the custodial Randall-Sundrum model with two Higgs doublets localized in the TeV brane. The scalar potential is CP- conserving and has a softly broken Z 2 symmetry. In the presence of a curvature-scalar mixing term ξ ab ℛΦ a †Φ b the radion that
Marco Merchand   +2 more
doaj   +1 more source

On the theory of generalized FC-groups

open access: yesJournal of Algebra, 2011
For each non-negative integer \(n\), the group class \(\text{FC}^n\) can be defined recursively in the following way: \(\text{FC}^0\) is the class of all finite groups, and a group \(G\) belongs to \(\text{FC}^{n+1}\) if \(G/C_G(\langle x\rangle^G)\) is an \(\text{FC}^n\)-group for every element \(x\) of \(G\).
Robinson D. J. S., Russo A., Vincenzi G.
openaire   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Gravitational waves from a Pati-Salam phase transition

open access: yesJournal of High Energy Physics, 2019
We analyse the gravitational wave and low energy signatures of a Pati-Salam phase transition. For a Pati-Salam scale of M PS ∼ 105 GeV, we find a stochastic power spectrum within reach of the next generation of ground-based interferometer experiments ...
Djuna Croon   +2 more
doaj   +1 more source

Plasmon Modes of Axisymmetric Metallic Nanoparticles: A Group Theory Analysis [PDF]

open access: yes, 2009
We report a thorough and rigorous analysis of the plasmon modes of axisymmetric metallic nanoparticles, based on group theory techniques and block diagonalization of the scattering T matrix.
Gantzounis, G.
core  

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