Results 71 to 80 of about 914,946 (318)
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Conformal invariance in the long-range Ising model
Nuclear Physics B, 2016 We consider the question of conformal invariance of the long-range Ising model at the critical point. The continuum description is given in terms of a nonlocal field theory, and the absence of a stress tensor invalidates all of the standard arguments for
Miguel F. Paulos +3 more
doaj +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
On the Groups with Homogeneous Theory
Tsukuba Journal of Mathematics, 1998 If \(2\leq m < n\) then a structure \(M\) is \((m,n)\)-homogeneous if for any \(\bar{a},\bar{b} \in M^n\), \(\bar{a}\) and \(\bar{b}\) have the same type if and only if corresponding \(m\)-subtuples have the same type. A complete theory is \((m,n)\)-homogeneous if all its subtuples are.
openaire +2 more sources
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
DNA Sequence and Structure under the Prism of Group Theory and Algebraic Surfaces. [PDF]
Int J Mol Sci, 2022 Planat M +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Structural measures of personal networks predict migrants' cultural backgrounds: an explanation from Grid/Group theory. [PDF]
PNAS Nexus, 2022 Molina JL +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Group Theory of Syntactical Freedom in DNA Transcription and Genome Decoding. [PDF]
Curr Issues Mol Biol, 2022 Planat M +5 more
europepmc +1 more source