Results 31 to 40 of about 29,979,332 (265)

Effects of a Cognitive Rehabilitation Programme on the Independence Performing Activities of Daily Living of Persons with Dementia—A Pilot Randomized Controlled Trial

Brain Sciences, 2021
Background: In all types of dementia, cognitive abilities are affected, behaviour is altered and functional capacity is progressively lost. This cognitive deterioration manifests in the decrease of abilities required to perform the activities of daily ...
María Jiménez Palomares, María Victoria González López-Arza, Elisa María Garrido Ardila, Trinidad Rodríguez Domínguez, Juan Rodríguez Mansilla   +4 more
doaj   +1 more source

Acceptance and Commitment Therapy group for treatment-resistant participants: a randomized controlled trial [PDF]

, 2014
Acceptance and Commitment Therapy (ACT) is a theoretically coherent approach addressing common processes across a range of disorders. The aim of this study was to investigate the effectiveness of a group-based ACT intervention for ‘treatment-resistant ...
Clarke, Sue, James, Kirsty, Remington, Bob, Remington, B., James, K., Kingston, Jessica, Kingston, J., Bolderston, Helen   +7 more
core   +1 more source

A comprehensive atlas of Aggrecan, Versican, Neurocan and Phosphacan expression across time in wildtype retina and in retinal degeneration

Scientific Reports, 2022
As photoreceptor cells die during retinal degeneration, the surrounding microenvironment undergoes significant changes that are increasingly recognized to play a prominent role in determining the efficacy of therapeutic interventions.
A. Matsuyama, A. A. Kalargyrou, A. J. Smith, R. R. Ali, R. A. Pearson   +4 more
doaj   +1 more source

Assessment of the effect of angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in peritoneal dialysis patients: a systematic review and meta-analysis on clinical trials

Renal Replacement Therapy, 2019
Background Renin-angiotensin system inhibitors (RASIs), either angiotensin-converting enzyme inhibitors or angiotensin receptor blockers, are widely used in patients with non-dialysis chronic kidney disease, as a renin-angiotensin system (RAS) blockade ...
Minoru Ito, Yosuke Saka, Yusuke Kuroki, Kaoru Yasuda, Hiraku Tsujimoto, Yasushi Tsujimoto, Hidemichi Yuasa, Munekazu Ryuzaki, Yasuhiko Ito, Hidetomo Nakamoto   +9 more
doaj   +1 more source

Recent progress in stem cell and immune cell-based interventions for aging and age-related disorders

Frontiers in Aging
The extension of human lifespan has intensified the demand for developing more effective strategies to enhance quality of life. Age-related physiological decline and associated diseases now constitute significant societal challenges.
Li He, Donglei Han, Fenfen Zong, Yan Zhang, Zhongyang Han, Zenghui Xu, Zenghui Xu, Zenghui Xu   +7 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Moderating factors for the effectiveness of group art therapy for schizophrenia: secondary analysis of data from the MATISSE randomised controlled trial. [PDF]

, 2014
Although some studies suggest that art therapy may be useful in the treatment of negative symptoms of schizophrenia, a recent large trial of group art therapy found no clinical advantage over standard care, but the study population was heterogeneous and ...
Killaspy, H, Leurent, B, Angela Hoadley, Crawford, Mike J., David P. Osborn, Helen Killaspy, Hoadley, A, Leurent, Baptiste, Osborn, David P, Crawford, MJ, Diane Waller, Osborn, DP, Hoadley, Angela, King, Michael, Baptiste Leurent, Waller, Diane, Mike J. Crawford, Michael King, Waller, D, Crawford, Mike J, Killaspy, Helen, Osborn, David P., King, M   +22 more
core   +1 more source

Comparative analysis and process optimization for manufacturing CAR-T using the PiggyBac system derived from cryopreserved versus fresh PBMCs

Scientific Reports
Chimeric antigen receptor T (CAR-T) therapy holds promise for cancer treatment but faces challenges with using fresh patient cells, including manufacturing failures and logistical hurdles.
Zenghui Xu, Ruyue Wang, Yuanjian Xu, Ruijuan Qiu, Jiangrui Chen, Linfeng Liu, Qijun Qian   +6 more
doaj   +1 more source

Unleashing the potential of a low CpG Passer transposon for superior CAR-T cell therapy

Frontiers in Immunology
BackgroundTo date, the non-viral vector Chimeric Antigen Receptor (CAR) T cell preparation platform, exemplified by transposons, has demonstrated significant potential in tumor immunotherapy and yielded positive results in multiple clinical trials ...
Jianyao Zeng, Yan Sun, Yan Sun, Yuan Fang, Xiaodie Wang, Qian Huang, Pingjing Zhang, Meiqi Shao, Pei Wang, Jingbo Cheng, Meng Di, Tao Liu, Qijun Qian, Qijun Qian, Qijun Qian   +14 more
doaj   +1 more source

Outcomes after peritoneal dialysis catheter placement by laparoscopic surgery versus open surgery: systematic review and meta-analysis

Renal Replacement Therapy, 2019
Success in peritoneal dialysis (PD) requires a well-functioning catheter, and catheter placement at PD initiation is extremely important for long-term PD.
Tsutomu Sakurada, Atsushi Ueda, Daisuke Komukai, Kiyotaka Uchiyama, Yasushi Tsujimoto, Hidemichi Yuasa, Munekazu Ryuzaki, Yasuhiko Ito, Masashi Tomo, Hidetomo Nakamoto   +9 more
doaj   +1 more source