Results 51 to 60 of about 16,466,590 (349)

Randomized, Open-Label Phase 3 Study Evaluating Immunogenicity, Safety, and Reactogenicity of RSVPreF3 OA Coadministered with FLU-QIV-HD in Adults Aged ≥ 65

open access: yesInfectious Diseases and Therapy
Introduction Respiratory syncytial virus (RSV) and influenza pose major disease burdens in older adults due to an aging immune system and comorbidities; seasonal overlap exists between these infections.
Robert Buynak   +11 more
doaj   +1 more source

Group-velocity slowdown in a double quantum dot molecule [PDF]

open access: yes, 2013
The slowdown of optical pulses due to quantum-coherence effects is investigated theoretically for an "active material" consisting of InGaAs-based double quantum-dot molecules.
S. Michael, W. Chow, H. Schneider
semanticscholar   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Soliton families and resonant radiation in a micro-ring resonator near zero group-velocity dispersion.

open access: yesOptics Express, 2014
We report theoretical and numerical study of the dynamical and spectral properties of the conservative and dissipative solitons in micro-ring resonators pumped in a proximity of the zero of the group velocity dispersion. We discuss frequency and velocity
Carles Milián, D. V. Skryabin
semanticscholar   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Multifrequency Bessel beams with adjustable group velocity and longitudinal acceleration in free space

open access: yesNew Journal of Physics, 2022
The group velocity of an optical beam in free space is usually considered to be equal to the speed of light in vacuum. However, it has been recently realized that, by structuring the beam’s angular and temporal spectra, one can achieve well pronounced ...
P Hildén   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Group-velocity-controlled and gate-tunable directional excitation of polaritons in graphene-boron nitride heterostructures

open access: yes, 2018
A fundamental building block in nano-photonics is the ability to directionally excite highly squeezed optical mode dynamically, particularly with an electrical bias.
Baile Zhang (1718578)   +4 more
core   +1 more source

Interferometric methods for aberration-insensitive imaging and generation of light beams with controlled group velocity

open access: yes, 2023
Optical interferometry has many important applications in science and technology. For example, it is used to improve the performance of interferometric imaging systems, to detect weak signals in cosmology, to measure surface profiles and vibrations in ...
Ilina, Elena
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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