Results 71 to 80 of about 16,466,590 (349)
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Fourth order accurate compact scheme with group velocity control (GVC)
, 2001 For solving complex flow field with multi-scale structure higher order accurate schemes are preferred. Among high order schemes the compact schemes have higher resolving efficiency.
马延文 +2 more
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
THE CIRCULAR VELOCITY FUNCTION OF GROUP GALAXIES [PDF]
The Astrophysical Journal, 2014 A robust prediction of $Λ{\rm CDM}$ cosmology is the halo circular velocity function (CVF), a dynamical cousin of the halo mass function. The correspondence between theoretical and observed CVFs is uncertain, however: cluster galaxies are reported to exhibit a power-law CVF consistent with $N$-body simulations, but that of the field is distinctly ...
Abramson, Louis E. +4 more
openaire +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
JGEUnderstanding of Earth's subsurface is crucial for mitigating geological hazards, particularly earthquakes. A key parameter for subsurface characterization is the surface wave dispersion curve, which strongly reflects shear wave velocity (Vs) at various ...
Muhammad Fachrul Rozi Kurniawan +2 more
doaj +1 more source
Growth of a Wave-group when the Group-velocity is Negative
Nature, 1905 THE following may be of interest in connection with the recent discussion on the flow of energy in such cases.
H. Pocklington
semanticscholar +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Dispersion of nonlinear group velocity determines shortest envelope solitons [PDF]
, 2011 We demonstrate that a generalized nonlinear Schrödinger equation (NSE), that includes dispersion of the intensity-dependent group velocity, allows for exact solitary solutions.
Bandelow, Uwe +6 more
core +1 more source
Comment on ‘Evidence of slow-light effects from rotary drag of structured beams’
New Journal of Physics, 2014 The paper Wisniewski-Barker E et al (2013 New J. Phys. 15 083020) is intended to distinguish experimentally between two mechanisms of pulse delay in ruby and to provide evidence in favor of the slow-light model.
G G Kozlov +3 more
doaj +1 more source