Results 161 to 170 of about 13,132,379 (283)

Characteristics and Outcomes After General Anaesthesia in Elderly Patients: A Nationwide Cohort Study. [PDF]

Acta Anaesthesiol Scand
Risager BH, Mortensen SØ, Pælestik MB, Stankovic N, Lind PC, Andersen LW.   +5 more
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Cycloastragenol Attenuates Cisplatin-Induced Ovarian Toxicity in Rats: Associations With TERT Expression, Apoptotic Balance, and FOXO3a-mTOR-Related Signaling. [PDF]

J Biochem Mol Toxicol
Erol GNA, Yar AS, Kaplanoğlu GT.
europepmc   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Interest Groups: An Introduction [PDF]

This paper reviews public choice theories of interest groups.Interest groups; rent ...
Filip Palda
core  

Oral Antioxidant Provides Adjunctive Therapeutic Benefits Alongside Dexamethasone in a Rat Model of Endotoxin-Induced Uveitis. [PDF]

Vet Med Sci
Yang SJ, Kim JY.
europepmc   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Correction: Diagnostic accuracy of deep learning vs. human raters for detecting osteoporotic vertebral compression fractures in routine CT scans. [PDF]

Eur Radiol
Riedel EO, Schinz D, Keicher M, Rühling S, El Husseini M, Pellegrini C, Baum T, Dieckmeyer M, Malagutti L, Seeger I, Walburga AS, Wiestler B, Sollmann N, Löffler MT, Wagner A, Kirschke JS.   +15 more
europepmc   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Caddyshack in the Illawarra Shoalhaven: Evaluating a Multi-Platform Sexual Health Promotion Programme. [PDF]

Health Promot J Austr
Demant D, Stratten M, Adamson W, Percival N.   +3 more
europepmc   +1 more source