Results 41 to 50 of about 354,932 (255)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
On the residual and profinite closures of commensurated subgroups
, 2019 The residual closure of a subgroup $H$ of a group $G$ is the intersection of all virtually normal subgroups of $G$ containing $H$. We show that if $G$ is generated by finitely many cosets of $H$ and if $H$ is commensurated, then the residual closure of ...
Caprace, Pierre-Emmanuel +3 more
core +1 more source
Molecular Oncology, EarlyView.In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Guangdong nongye kexue【Objective】Plant AT-rich sequence and zinc-binding (PLATZ) transcription factors are plant-specific, zinc-dependent DNA-binding proteins that play a role in regulating plant growth and environmental stress responses. To clarify the characteristics of the
Xinqi CHEN +9 more
doaj +1 more source
Indicability, residual finiteness, and simple subquotients of groups acting on trees
, 2017 We establish three independent results on groups acting on trees. The first implies that a compactly generated locally compact group which acts continuously on a locally finite tree with nilpotent local action and no global fixed point is virtually ...
Caprace, Pierre-Emmanuel +1 more
core +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
High transitivity for more groups acting on trees
, 2020 We establish a new sharp sufficient condition for groups acting on trees to be highly transitive. This give new examples of highly transitive groups, including icc non-solvable Baumslag-Solitar groups, thus answering a question of Hull and Osin.Comment ...
Fima, Pierre +3 more
core
L^2-Betti numbers and Plancherel measure
, 2013 We compute $L^2$-Betti numbers of postliminal, locally compact, unimodular groups in terms of ordinary dimensions of reduced cohomology with coefficients in irreducible unitary representations and the Plancherel measure.
Petersen, Henrik Densing, Valette, Alain
core +1 more source
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source