Results 51 to 60 of about 628,106 (241)

Effect of a low glycaemic index diet during pregnancy on maternal and cord blood metabolomic profiles: results from the ROLO randomized controlled trial

open access: yesNutrition & Metabolism, 2019
Background Elevated post-prandial blood glucose during pregnancy has been associated with adverse pregnancy and offspring outcomes, such as maternal gestational diabetes and excessive foetal growth.
Linda Marchioro   +6 more
doaj   +1 more source

International effort toward a SSR-based linkage map for C. clementina : [P128] [PDF]

open access: yes, 2008
Following the difficulties encountered for assembling a 1.2 x sequencing of the highly heterozygous sweet orange genome, the International Citrus Genomic Consortium (ICOC) decided to estab1ish the first reference sequence of a whole nuclear citrus genome
Billot, Claire   +17 more
core  

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Introduction to Sofic and Hyperlinear groups and Connes' embedding conjecture

open access: yes, 2015
Sofic and hyperlinear groups are the countable discrete groups that can be approximated in a suitable sense by finite symmetric groups and groups of unitary matrices.
Capraro, Valerio, Lupini, Martino
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Toward Nutritionally Sound Plant-Based Meat Analogues: Expert Consensus from a Delphi Study

open access: yesFoods
Plant-based diets are increasingly recognized for their potential health benefits, reduced environmental impact, and alignment with ethical concerns related to animal welfare.
Nathalia Tarossi Locatelli   +4 more
doaj   +1 more source

Unstable Adams operations on p-local compact groups

open access: yes, 2011
A p-local compact group is an algebraic object modelled on the p-local homotopy theory of classifying spaces of compact Lie groups and p-compact groups. In the study of these objects unstable Adams operations, are of fundamental importance. In this paper
Assaf Libman   +8 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Soil infiltration variability across diverse soil reference groups, textures, and landuse types

open access: yesGeoderma
Soil infiltration, a key process in the terrestrial water cycle, is typically measured pointwise, but is often upscaled by averaging across different soil groups or even texture classes, e.g., when parameterizing water movement in land surface models. We
Farnaz Sharghi S.   +5 more
doaj   +1 more source

Chemical composition, sensory characteristics, and fatty acid profile of muscle from Aberdeen Angus, Charolais, Simmental, and Hereford bulls

open access: yesCzech Journal of Animal Science, 2006
Aberdeen Angus (AA), Charolais (CH), Simmental (SI), and Hereford (HE) bulls were used in two fattening experiments with the objective of determining breed differences in chemical composition, sensory characteristics, and fatty acid profile of m ...
D. Bureš   +4 more
doaj   +1 more source

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