Results 31 to 40 of about 178,758 (268)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Algebraic lattices of solvably saturated formations and their applications

open access: yes, 2021
In each group G, we select a system of subgroups τ(G) and say that τ is a subgroup functor if G∈τ(G) for every group G, and for every epimorphism φ:A→B and any H∈τ(A) and T∈τ(B), we have Hφ∈τ(B) and Tφ−1∈τ(A).
Tsarev, Aleksandr, Kukharev, Andrei
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Schistosoma mansoni Adult Worm Protective and Diagnostic Proteins in n-Butanol Extracts Revealed by Proteomic Analysis

open access: yesPathogens, 2021
The S. mansoni adult worm n-butanol extract (Sm-AWBE) has been previously shown to contain specific S. mansoni antigens that have been used for immunodiagnosis of schistosomiasis in solid phase alkaline phosphatase immunoassay (APIA) and western blot (WB)
Guidenn Sulbarán   +4 more
doaj   +1 more source

Injectors in Fitting sets of finite groups [PDF]

open access: yes, 2015
A set of subgroups F of a finite group G is referred to as a Fitting set if it is closed with respect to taking normal subgroups, products of normal F-subgroups, and inner automorphisms of G.
Vorobev, N. T., Semenov, M. G.
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Evolution of Model Compounds and Functional Group Compositions for Molecular Dynamics Simulations of Aged Asphalt Binder

open access: yesMolecules
To apply molecular dynamics (MD) simulations in the study of virgin asphalt binder, researchers have relied on basis sets of representative model structures from the SARA categories of saturated aliphatics (S), naphthenic aromatics (A), polar aromatics ...
Edgar A. O’Rear   +2 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Mechanism of MoO3 dispergation on SiO2 surface

open access: yesХімія, фізика та технологія поверхні
Molybdena dispergation on silica surface via heat treatment of dry mixtures of MoO3 and the dispersed silica support is a convenient preparative technique of the synthesis of surface Mo(VI) oxo-species.
D.B. Nasiedkin   +3 more
doaj   +3 more sources

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