Results 141 to 150 of about 311,005 (248)

Warming trends and shortened growing seasons: integrating four decades of observations and model simulations to develop wheat adaptation strategies in semi-arid Pakistan. [PDF]

Sci Rep
Ahmed M, Sameen A, Kheir AMS.
europepmc   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

A Comparative Study of Phenolics in Green Husks of Selected Hungarian Walnut Cultivars. [PDF]

Plants (Basel)
Kithi L, Szanics EH, Berki M, Lengyel-Kónya É, Tömösközi-Farkas R, Benes E, Ficzek G, Krasniqi V, Bujdosó G.   +8 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Predicting current and future areas of ecological suitability for Lutzomyia longipalpis sensu lato in the Americas. [PDF]

J Med Entomol
DeWinter S, Nichol GK, Fernandez Prada C, Greer AL, Weese JS, Clow KM.   +5 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Phylogenetic signal in flowering phenology weakens over elevation in the high Andes of Chile: evidence for evolutionary convergence in a harsh habitat. [PDF]

Front Plant Sci
Tamburrino Í, Robles V, Jara-Arancio P, Guerrero PC, López-Angulo J, Cavender-Bares J, Arroyo MTK.   +6 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Novel Chitosan Bioink Derived from <i>Eurycantha calcarata</i> (Lucas, 1869) for 3D Bioprinting of Cell-Compatible Scaffolds. [PDF]

ACS Omega
Mei Z, Lagouarde J, Volkova O, Baylot V, Candet C, Barthélémy P, Kuzhir P, Godeau G.   +7 more
europepmc   +1 more source