Results 121 to 130 of about 1,552,234 (302)
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Assessing quality and total quality in economic higher education [PDF]
Nowadays, there are countries, systems and cultures where the issue of quality management and all the items implied are firmly on the agenda for higher education institutions.
Catalina Sitnikov
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Crossroads Rhode Island: Proposed Social Enterprise Business Plan [PDF]
, 2014 Crossroads Rhode Island provides their clients with a continuum of care that includes basic emergency needs, shelter, housing, case management and vocational services for individuals and families.
Brookes, Joe +5 more
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
The myExperiment Open Repository for Scientific Workflows [PDF]
, 2009 4th International Conference on Open RepositoriesThis presentation was part of the session : Conference PresentationsDate: 2009-05-19 10:00 AM – 11:30 AMmyExperiment is an open repository solution for the born-digital items arising in contemporary ...
Aleksejevs, Sergejs +7 more
core +1 more source
Molecular Oncology, EarlyView.Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad +35 more
wiley +1 more source
To choose or not to choose: how to deal with China's growing power and influence [PDF]
This paper collects 10 items published on the ASPI blog The Strategist by eight authors on one of the most important public policy issues of this decade and beyond: how to deal with China’s growing power and influence.
Andrew O' +7 more
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, 1956 An analysis of commercial farming in Alaska has long been needed. This report may supply helpful information. It spans the yea rs from 1949 to 1954, a time of rapid development and growth. T he study analyzes detailed information supplied by 75 to 85
Andrews, Richard A., Johnson, Hugh A.
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Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Results From the Long-Term Inmate Survey: Focus on Child Abuse Histories [PDF]
, 1998 This report of long-term inmates in Alaska correctional facilities attempts to describe the childhood experiences of a sample of long-term inmates, address the "cycle of abuse" issue; and present the correlates of abuse which may impact the pattern of ...
Barnes, Allan R. +2 more
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