Results 91 to 100 of about 9,378,575 (316)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1429-1452, June 2026.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1398-1419, June 2026.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Orthodontic treatment : management of unfavorable sequelae

open access: yes, 1996
http://babel.hathitrust.org/cgi/pt?id=mdp.39015037267435;view=2up;ui=fullscreen#page/n0/mode ...
Symposium on Craniofacial Growth   +2 more
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1626-1642, June 2026.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Export-led Growth

open access: yes
Growth Lab Working Paper Series No. 231In this paper, I argue that a focus on exports, both at the intensive margin (where existing products increase their volume), but especially at the extensive margin (where new products start being exported), can ...
Hausmann, Ricardo
core  

Taking advantage of emerging technologies in clinical practice

open access: yes, 2012
http://babel.hathitrust.org/cgi/pt?id=mdp.39015100641854;view=2up;ui=fullscreen#page/n0/mode ...
Moyers Symposium   +3 more
core  

Accelerating Guatemala Growth

open access: yes, 2013
Guatemala is the largest economy in Central America, with a GDP of US$46.9 billion (2011). A moderate long-term rate of economic growth of 3.3 percent between 2001 and 2011 translated into a per capita GDP of
The Growth Dialogue
core   +1 more source

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