Results 91 to 100 of about 23,882,396 (395)

A nanobody-based toolset to investigate the role of protein localization and dispersal in Drosophila

open access: yeseLife, 2017
The role of protein localization along the apical-basal axis of polarized cells is difficult to investigate in vivo, partially due to lack of suitable tools.
Stefan Harmansa   +4 more
doaj   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Strain Engineering of Ferroelectric Domains in KxNa1−xNbO3 Epitaxial Layers

open access: yesFrontiers in Materials, 2017
The application of lattice strain through epitaxial growth of oxide films on lattice mismatched perovskite-like substrates strongly influences the structural properties of ferroelectric domains and their corresponding piezoelectric behavior.
Jutta Schwarzkopf   +4 more
doaj   +1 more source

TSC2 mediates cellular energy response to control cell growth and survival.

open access: yesCell, 2003
Mutations in either the TSC1 or TSC2 tumor suppressor gene are responsible for Tuberous Sclerosis Complex. The gene products of TSC1 and TSC2 form a functional complex and inhibit the phosphorylation of S6K and 4EBP1, two key regulators of translation ...
K. Inoki, Tianqing Zhu, K. Guan
semanticscholar   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Investigating the Relationship between Nocturnal Enuresis and Sleep Disordered Breathing Using Polysomnography Data of 5-10 Year-Old Children Referred to Qazvin Children's Hospital, Iran

open access: yesJournal of Sleep Sciences
Background and Objective: Sleep is a critical biological necessity essential for maintaining both physical and mental health in humans. Given the prevalence of nocturnal enuresis (NE) in children, this study sought to explore its potential link to sleep-
Shabnam Jalilolghadr   +5 more
doaj   +1 more source

An Integrated Landscape Approach for Socially Inclusive Peatland Restoration

open access: yesJournal of Wetlands Environmental Management, 2020
Successful restoration and fire prevention in peat landscapes require full rewetting and permanent revegetation for optimal water retention. The ecological and socio-economic heterogeneity of these landscapes calls for integrated approaches based on ...
Timothy Jessup   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

RelA Inhibits Embryonic Myogenesis by Coordinately Regulating a Novel Distal Enhancer of Myogenin

open access: yesAdvanced Science
Skeletal muscle is crucial for lifelong metabolic health, with its development initiating during embryogenesis and guiding later growth. Single‐cell RNA sequencing of E13.5 mouse embryos suggests that maternal obesity impairs embryonic myogenesis ...
Md Nazmul Hossain   +9 more
doaj   +1 more source

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