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Growth Hormone, Not Simply Just a Hormone for Growth [PDF]

Endocrinology and Metabolism
Since its discovery almost 100 years ago, growth hormone (GH) has been extensively studied to elucidate its structural characteristics, receptor interactions and its physiologic and non-physiologic effects.
Kevin C. J. Yuen, Jaime Guevara-Aguirre, John J. Kopchick   +2 more
doaj   +2 more sources

Adult growth hormone deficiency – benefits, side effects, and risks of growth hormone replacement

Frontiers in Endocrinology, 2013
Deficiency of growth hormone (GH) in adults results in a syndrome characterized by decreased muscle mass and exercise capacity, increased visceral fat, impaired quality of life, unfavorable alterations in lipid profile and markers of cardiovascular risk,
Mary Lim Reed, George R. Merriam, Atil Y Kargi   +2 more
doaj   +3 more sources

Molecular Basis for Hypochondroplasia in Japan

Endocrines, 2022
Hypochondroplasia is an autosomal dominant genetic disorder due to a heterozygous pathogenic variant of the FGFR3 gene. The early diagnosis of hypochondroplasia is necessary, since growth hormone is effective for improving adult height.
Tomohiro Ishii, Masaki Takagi, Keisuke Nagasaki, Toshio Ohara, Kentaro Miyai, Tomoki Kosho, Fumio Takada, Gen Nishimura, Tomonobu Hasegawa   +8 more
doaj   +1 more source

Biochemical identification of prepubertal boys with Klinefelter syndrome by combined reproductive hormone profiling using machine learning

Endocrine Connections, 2023
Objective: Klinefelter syndrome (KS) is the most common sex chromosome disorder and genetic cause of infertility in males. A highly variable phenotype contributes to the fact that a large proportion of cases are never diagnosed.
Andre Madsen, Anders Juul, Lise Aksglaede   +2 more
doaj   +1 more source

Response to growth hormone according to provocation test results in idiopathic short stature and idiopathic growth hormone deficiency [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2022
Purpose To investigate growth response in children with either idiopathic short stature (ISS) or growth hormone (GH) deficiency (GHD). Methods The data of prepubertal GHD or ISS children treated using recombinant human GH were obtained from the LG Growth
Ju Young Yoon, Chong Kun Cheon, Jung Hyun Lee, Min Jung Kwak, Hyun-Ji Kim, Ye Jin Kim, Jeong Eun Lee, Woo Yeong Chung, Jeongyun Kim, Jae-Ho Yoo   +9 more
doaj   +1 more source

An improved strategy to analyse strigolactones in complex sample matrices using UHPLC–MS/MS

Plant Methods, 2020
Background Strigolactones represent the most recently described group of plant hormones involved in many aspects of plant growth regulation. Simultaneously, root exuded strigolactones mediate rhizosphere signaling towards beneficial arbuscular ...
Kristýna Floková, Mahdere Shimels, Beatriz Andreo Jimenez, Nicoletta Bardaro, Miroslav Strnad, Ondřej Novák, Harro J. Bouwmeester   +6 more
doaj   +1 more source

Growth hormone treatment in non-growth hormone-deficient children [PDF]

Annals of Pediatric Endocrinology & Metabolism, 2014
Until 1985 growth hormone (GH) was obtained from pituitary extracts, and was available in limited amounts only to treat severe growth hormone deficiency (GHD).
Sandro Loche, Luisanna Carta, Anastasia Ibba, Chiara Guzzetti   +3 more
doaj   +1 more source

Effects of zearalenone on ovarian development of prepubertal gilts through growth hormone axis

Frontiers in Veterinary Science, 2022
This experiment aimed to establish the effects of zearalenone (ZEN) on ovarian development in prepubertal gilts through the growth hormone axis [growth hormone-releasing hormone (GHRH) / growth hormone (GH) / growth hormone receptor (GHR)].
Fengyang Wu, Lijie Gao, Fei Li, Jia Cui, Xinyu Yang, Yanhua Liu, Saijuan Chen, Saijuan Chen, Baojiang Chen   +8 more
doaj   +1 more source

Consensus guidelines for the diagnosis and treatment of adults with growth hormone deficiency: Summary statement of the growth hormone research society workshop on adult growth hormone deficiency [PDF]

, 1998
Based on the increasing body of evidence that adults with GH deficiency (somatotropin deficiency) have impaired health that improves with GH replacement, many countries have already approved the use of GH for replacement therapy in adults with GH ...
Growth Hormone Research Society Workshop on Adult Growth Hormone Deficiency, Clemmons, David   +1 more
core   +1 more source

Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation [PDF]

, 2010
Study found that treatment with recombinant human growth hormone gave significantly greater benefits in stature for children with growth hormone deficiency (GHD), Turner syndrome, Prader–Willi syndrome, chronic renal insufficency, short stature homeobox ...
Bird, A., Baxter, L, Gospodarevskaya, E., K Welch, Cooper, Keith, L Baxter, Frampton, G. K., A Bird, Frampton, GK, Gospodarevskaya, Elena, Gospodarevskaya, E, Welch, K, Bryant, J, Takeda, A, Frampton, G.K., Cooper, K., GK Frampton, Takeda, Andrea, Bird, A, Bryant, J., J Bryant, K Cooper, Welch, Karen, Welch, K., Baxter, L., Takeda, A., Bryant, Jackie, A Takeda, E Gospodarevskaya, Cooper, K   +29 more
core   +1 more source