Novel mechanisms of growth hormone regulation: growth hormone-releasing peptides and ghrelin [PDF]
Brazilian Journal of Medical and Biological Research, 2006 Growth hormone secretion is classically modulated by two hypothalamic hormones, growth hormone-releasing hormone and somatostatin. A third pathway was proposed in the last decade, which involves the growth hormone secretagogues.
A.-M.J. Lengyel
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Growth hormone-releasing hormone receptor signaling in experimental ocular inflammation and neuroprotection [PDF]
Neural Regeneration Research, 2022 Both inflammation and anti-inflammation are involved in the protection of retinal cells. Antagonists of the hypothalamic growth hormone-releasing hormone receptor (GHRHR) have been shown to possess potent anti-inflammatory properties in experimental ...
Ling-Ping Cen +3 more
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Growth Hormone-Releasing Hormone in Diabetes [PDF]
Frontiers in Endocrinology, 2016 Growth hormone-releasing hormone (GHRH) is produced by the hypothalamus and stimulates growth hormone synthesis and release in the anterior pituitary gland.
Leonid Evsey Fridlyand +3 more
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Acromegaly Caused by Ectopic Growth Hormone Releasing Hormone Secretion: A Review [PDF]
Frontiers in Endocrinology, 2022 IntroductionEctopic acromegaly is a rare condition caused most frequently by growth hormone releasing hormone (GHRH) secretion from neuroendocrine tumors.
Iga Zendran +4 more
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Growth hormone releasing hormone signaling promotes Th17 cell differentiation and autoimmune inflammation [PDF]
Nature Communications, 2023 Dysregulation of Th17 cell differentiation and pathogenicity contributes to multiple autoimmune and inflammatory diseases. Previously growth hormone releasing hormone receptor (GHRH-R) deficient mice have been reported to be less susceptible to the ...
Lin Du +11 more
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VMN growth hormone-releasing hormone receptor regulation of counterregulatory transmission [PDF]
Academia BiologyVentromedial hypothalamic nucleus (VMN) growth hormone-releasing hormone (Ghrh) neurotransmission governs counterregulatory hormone release.
Subash Sapkota +4 more
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The Decreased Growth Hormone Response to Growth Hormone Releasing Hormone in Obesity Is Associated to Cardiometabolic Risk Factors [PDF]
Mediators of Inflammation, 2010 The aim of the present study was to evaluate the relationship between GHRH-induced GH secretion in obese premenopausal women and cardiovascular risk markers or insulin resistance. Premenopausal obese women, aged 35–52 years, were studied.
Fernando Cordido +4 more
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Growth hormone-releasing hormone in retinal disorders and uveitis: an updated review [PDF]
International Journal of OphthalmologyGrowth hormone-releasing hormone (GHRH) is a hypothalamic releasing hormone that plays a crucial physiological role in regulating the synthesis and release of anterior pituitary hormones.
Sha-Lin Yi, Yu-Qiang Huang
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Synthesis and characterization of novel ssDNA X-aptamers targeting Growth Hormone Releasing Hormone (GHRH). [PDF]
PLoS ONE, 2022 BackgroundGrowth Hormone Releasing Hormone (GHRH), 44 amino acids containing hypothalamic hormone, retains the biological activity by its first 29 amino acids.
Burcu Ayhan-Sahin +4 more
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Growth hormone-releasing hormone agonist attenuates vascular calcification in diabetic db/db mice [PDF]
Frontiers in Cardiovascular Medicine, 2023 IntroductionVascular calcification (VC) is an independent risk factor for cardiovascular diseases. VC increases mortality of all-causes. VC is one of most common cardiovascular complications in type II diabetes.
Hao-Lin Ren +18 more
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