Results 1 to 10 of about 5,646,776 (202)

Growth hormone response to growth hormone-releasing peptide-2 in growth hormone-deficient Little mice

Clinics, 2012
OBJECTIVE: To investigate a possible direct, growth hormone-releasing, hormone-independent action of a growth hormone secretagogue, GHRP-2, in pituitary somatotroph cells in the presence of inactive growth hormonereleasing hormone receptors.
Cibele N. Peroni, Cesar Y. Hayashida, Nancy Nascimento, Viviane C. Longuini, Rodrigo A. Toledo, Paolo Bartolini, Cyril Y. Bowers, Sergio P.A. Toledo   +7 more
doaj   +2 more sources

Growth hormone-releasing hormone receptor signaling in experimental ocular inflammation and neuroprotection

Neural Regeneration Research, 2022
Both inflammation and anti-inflammation are involved in the protection of retinal cells. Antagonists of the hypothalamic growth hormone-releasing hormone receptor (GHRHR) have been shown to possess potent anti-inflammatory properties in experimental ...
Ling-Ping Cen, Tsz Kin Ng, Wai Kit Chu, Chi Pui Pang   +3 more
doaj   +2 more sources

Effect of growth hormone releasing hormone on chondrocytes of osteoarthritis [PDF]

The Korean Journal of Internal Medicine, 2022
Background/Aims To evaluate the effect and possible mechanism of growth hormone releasing hormone (GHRH) on chondrocytes of osteoarthritis (OA). Methods Articular chondrocytes were cultured and the expression of GHRH receptor in chondrocytes was detected.
Zhuoran LI, Yao LI
doaj   +1 more source

Effects of zearalenone on ovarian development of prepubertal gilts through growth hormone axis

Frontiers in Veterinary Science, 2022
This experiment aimed to establish the effects of zearalenone (ZEN) on ovarian development in prepubertal gilts through the growth hormone axis [growth hormone-releasing hormone (GHRH) / growth hormone (GH) / growth hormone receptor (GHR)].
Fengyang Wu, Lijie Gao, Fei Li, Jia Cui, Xinyu Yang, Yanhua Liu, Saijuan Chen, Saijuan Chen, Baojiang Chen   +8 more
doaj   +1 more source

Acromegaly Caused by Ectopic Growth Hormone Releasing Hormone Secretion: A Review

Frontiers in Endocrinology, 2022
IntroductionEctopic acromegaly is a rare condition caused most frequently by growth hormone releasing hormone (GHRH) secretion from neuroendocrine tumors.
Iga Zendran, Gabriela Gut, Marcin Kałużny, Katarzyna Zawadzka, Marek Bolanowski   +4 more
doaj   +1 more source

Synthesis and characterization of novel ssDNA X-aptamers targeting Growth Hormone Releasing Hormone (GHRH).

PLoS ONE, 2022
BackgroundGrowth Hormone Releasing Hormone (GHRH), 44 amino acids containing hypothalamic hormone, retains the biological activity by its first 29 amino acids.
Burcu Ayhan-Sahin, Zeynep-Elif Apaydın, Pınar Obakan-Yerlikaya, Elif-Damla Arisan, Ajda Coker-Gurkan   +4 more
doaj   +2 more sources

Advanced bone age as an indicator facilitates the diagnosis of precocious puberty

Jornal de Pediatria, 2018
Objective: Diagnosis of central precocious puberty has always been challenging in clinical practice. As an important method in the diagnosis of central precocious puberty, luteinizing hormone-releasing hormone stimulation test is complex and time ...
Yue-Qin Xu, Gui-Mei Li, Yan Li
doaj   +3 more sources

Growth Hormone-Releasing Hormone in Lung Physiology and Pulmonary Disease

Cells, 2020
Growth hormone-releasing hormone (GHRH) is secreted primarily from the hypothalamus, but other tissues, including the lungs, produce it locally.
Chongxu Zhang, Tengjiao Cui, Renzhi Cai, Medhi Wangpaichitr, Mehdi Mirsaeidi, Andrew V. Schally, Robert M. Jackson   +6 more
doaj   +1 more source

Growth Hormone-Releasing Hormone in Diabetes

Frontiers in Endocrinology, 2016
Growth hormone-releasing hormone (GHRH) is produced by the hypothalamus and stimulates growth hormone synthesis and release in the anterior pituitary gland.
Leonid Evsey Fridlyand, Natalia A Tamarina, Andrew V Schally, Louis H Philipson   +3 more
doaj   +1 more source

Growth hormone releasing hormone signaling promotes Th17 cell differentiation and autoimmune inflammation

Nature Communications, 2023
Dysregulation of Th17 cell differentiation and pathogenicity contributes to multiple autoimmune and inflammatory diseases. Previously growth hormone releasing hormone receptor (GHRH-R) deficient mice have been reported to be less susceptible to the ...
Lin Du, Bo Man Ho, Linbin Zhou, Yolanda Wong Ying Yip, Jing Na He, Yingying Wei, Clement C. Tham, Sun On Chan, Andrew V. Schally, Chi Pui Pang, Jian Li, Wai Kit Chu   +11 more
doaj   +1 more source