Wellness-enhancing effects of the canine growth hormone releasing hormone therapy mediated by plasmid and electroporation in healthy old dogs [PDF]
Frontiers in Veterinary ScienceAging leads to increased disease susceptibility and weakened immunity, a condition known as immunosenescence. The growth hormone-releasing hormone (GHRH)/growth hormone (GH)/insulin-like growth factor 1 (IGF-1) axis plays a key role in both somatic ...
Min-Ok Ryu +9 more
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Protective Activities of Growth Hormone-Releasing Hormone Antagonists against Toxin-Induced Endothelial Injury [PDF]
EndocrinesGHRH regulates the secretion of GH from the anterior pituitary gland, previously associated with cancer progression and inflammation. An emerging body of evidence suggests that GHRHAnt support endothelial barrier function, but the mechanisms mediating ...
Saikat Fakir, Nektarios Barabutis
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Growth hormone – releasing hormone in the context of inflammation and redox biology [PDF]
Frontiers in ImmunologyAgnieszka Siejka, Nektarios Barabutis
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Effect of growth hormone releasing hormone on chondrocytes of osteoarthritis [PDF]
The Korean Journal of Internal Medicine, 2022 Background/Aims To evaluate the effect and possible mechanism of growth hormone releasing hormone (GHRH) on chondrocytes of osteoarthritis (OA). Methods Articular chondrocytes were cultured and the expression of GHRH receptor in chondrocytes was detected.
Zhuoran LI, Yao LI
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Growth Hormone-Releasing Hormone*
Endocrine Reviews, 1986 The identification of GRH has been followed by an extraordinarily rapid rate of knowledge accumulation. Within a period of slightly more than 3 yr since the structure of the GRH was determined, nearly 500 papers have been published pertaining to the hormone. Extensive knowledge of its anatomy, chemistry, molecular biology, physiology, and pathology has
L A, Frohman, J O, Jansson
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Ghrelin Decreases Firing Activity of Gonadotropin-Releasing Hormone (GnRH) Neurons in an Estrous Cycle and Endocannabinoid Signaling Dependent Manner. [PDF]
, 2013 The orexigenic peptide, ghrelin is known to influence function of GnRH neurons, however, the direct effects of the hormone upon these neurons have not been explored, yet.
Farkas, Imre +3 more
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Effects of zearalenone on ovarian development of prepubertal gilts through growth hormone axis
Frontiers in Veterinary Science, 2022 This experiment aimed to establish the effects of zearalenone (ZEN) on ovarian development in prepubertal gilts through the growth hormone axis [growth hormone-releasing hormone (GHRH) / growth hormone (GH) / growth hormone receptor (GHR)].
Fengyang Wu +8 more
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Advanced bone age as an indicator facilitates the diagnosis of precocious puberty
Jornal de Pediatria, 2018 Objective: Diagnosis of central precocious puberty has always been challenging in clinical practice. As an important method in the diagnosis of central precocious puberty, luteinizing hormone-releasing hormone stimulation test is complex and time ...
Yue-Qin Xu, Gui-Mei Li, Yan Li
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Growth Hormone-Releasing Hormone in Lung Physiology and Pulmonary Disease
Cells, 2020 Growth hormone-releasing hormone (GHRH) is secreted primarily from the hypothalamus, but other tissues, including the lungs, produce it locally.
Chongxu Zhang +6 more
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Growth Hormone (GH)-Releasing Peptide Stimulation of GH Release from Human Somatotroph Adenoma Cells: Interaction with GH-Releasing Hormone, Thyrotropin- Releasing Hormone, and Octreotide. [PDF]
, 1994 The synthetic hexapeptide GH-releasing peptide (GHRP; His-D-Trp-Ala-Trp-D-Phe-Lys-NH2) specifically stimulates GH secretion in humans in vivo and in animals in vitro and in vivo via a still unknown receptor and mechanism.
Brockmeier, S. +7 more
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