Results 21 to 30 of about 4,600,437 (268)

Vitamin D Metabolism and Effects on Pluripotency Genes and Cell Differentiation in Testicular Germ Cell Tumors In Vitro and In Vivo

Neoplasia: An International Journal for Oncology Research, 2012
Testicular germ cell tumors (TGCTs) are classified as either seminomas or nonseminomas. Both tumors originate from carcinoma in situ (CIS) cells, which are derived from transformed fetal gonocytes.
Martin Blomberg Jensen, Anne Jørgensen, John Erik Nielsen, Andreas Steinmeyer, Henrik Leffers, Anders Juul, Ewa Rajpert-De Meyts   +6 more
doaj   +1 more source

Dynamic formation and transcriptional regulation mediated by phytohormones during chalkiness formation in rice

BMC Plant Biology, 2021
Background Rice (Oryza sativa L.) Chalkiness, the opaque part in the kernel endosperm formed by loosely piled starch and protein bodies. Chalkiness is a complex quantitative trait regulated by multiple genes and various environmental factors ...
Qin Xie, Jinke Xu, Ke Huang, Yi Su, Jianhua Tong, Zhigang Huang, Chao Huang, Manlin Wei, Wanhuang Lin, Langtao Xiao   +9 more
doaj   +1 more source

Growth, growth factors and diabetes [PDF]

European Journal of Endocrinology, 2004
Type 1 diabetes mellitus (T1DM) and other chronic diseases in children are well known to adversely affect linear growth and pubertal development. In the years immediately following the introduction of insulin therapy, short stature was consistently reported in children with T1DM.
CHIARELLI, Francesco, Giannini C, MOHN, Angelika Anna   +2 more
openaire   +4 more sources

Health‐Related Social Needs in Children With Sickle Cell Disease Are Associated With Worse Health‐Related Quality of Life

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell disease (SCD) face multiple acute and chronic medical complications that may impact their quality of life as reported by patients themselves. Health‐related social needs (HRSNs), such as food and housing insecurity, are common in people with SCD, but the association between HRSNs and patient‐reported ...
Sarah J. Marks, Molly Sonenklar, Cerelia Donald, Cecelia Valrie, Wally Smith, India Sisler   +5 more
wiley   +1 more source

Child nutrition to new stage in China: evidence from a series of national surveys, 1985–2015

BMC Public Health, 2019
Background Both child under- and over-nutrition are major global public health challenges. We aimed to examine thirty-year trends in physical growth, under- and over-nutrition in Chinese urban and suburban children between 1985 and 2015, and discuss ...
Xin-Nan Zong, Hui Li, Ya-Qin Zhang, Hua-Hong Wu   +3 more
doaj   +1 more source

Cup‐Like Nuclei Is a Hallmark of DUX4/ERG Acute Lymphoblastic Leukemia and Reveals Cytoplasmic Mitochondria Accumulation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille, Hugo Roux, Odile Fenneteau, Aurélie Caye‐Eude, Alexia Kinoo, Yoann Vial, André Baruchel, Marion Strullu, Elodie Lainey, Hélène Cavé   +9 more
wiley   +1 more source

Charcoal kiln sites, associated landscape attributes and historic forest conditions: DTM-based investigations in Hesse (Germany)

Forest Ecosystems, 2016
Background An examination of the distribution of ancient charcoal kiln sites in the forest landscape seems to be worthwhile, since general trends in the selection of suitable kiln site locations in the past might become obvious.
Marcus Schmidt, Andreas Mölder, Egbert Schönfelder, Falko Engel   +3 more
doaj   +1 more source

Self-Reported Asthma Is Associated with Reduced Sperm Count—A Cross-Sectional Study of More than 6000 Young Men from the General Population

Life, 2023
Asthma is driven by an inflammatory response that may impact testicular function. In this cross-sectional study, we investigated the association between self-reported asthma and testicular function (semen parameters, reproductive hormone levels), and ...
Marc K. Pedersen, Elvira V. Bräuner, Ann H. Hansen, Laura S. Hansen, Tina K. Jensen, Niels Jørgensen, Lærke Priskorn   +6 more
doaj   +1 more source

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian, Yannick Braun, Till‐Martin Theilen, Anke Barnbrock, Theresa Rohm, Fabienne Hammant, Nicole Sänger, Aynura Abbasova‐Semiz, Jan‐Henning Klusmann, Thomas Klingebiel, Udo Rolle, Peter Bader, Henning C. Fiegel, Andrea Jarisch   +13 more
wiley   +1 more source

Rational Use of Herbal Products in Pediatric Patients Treated With Anticancer Drugs in the European Union

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot, Mathieu Corvaisier, Laurence Spiesser‐Robelet, Mylène Duplan, Isabelle Pellier, Delphine Bourneau‐Martin, Séverine Derbré   +6 more
wiley   +1 more source