Results 41 to 50 of about 4,600,437 (268)
USP5-Beclin 1 axis overrides p53-dependent senescence and drives Kras-induced tumorigenicity
Nature Communications, 2022 Oncogene-induced senescence (OIS) occurs in premalignant lung adenomas, but infrequently in malignant adenocarcinomas. Here the authors show that USP5-Beclin 1 axis overcomes OIS in Kras-driven lung cancer by enhancing MDM2-mediated p53 degradation.
Juan Li +15 more
doaj +1 more source
Growth in Studying the Cessation of Growth [PDF]
Journal of Bacteriology, 1999 Having been asked to write a guest commentary for the Journal of Bacteriology as part of the year-long commemoration of the American Society for Microbiology (ASM) centennial, how does one proceed? Having been asked to write about the change in mind-set that led molecular microbiologists to begin exploring the molecular mechanisms at play in the ...
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Platinum‐based chemotherapy is known to cause severe and debilitating hearing loss, but unlike cisplatin, the true incidence of carboplatin‐induced hearing loss remains unclear. We evaluated functional hearing outcomes in children receiving carboplatin to determine the incidence and severity of ototoxicity. Procedure We identified a
Aniket Chawla +6 more
wiley +1 more source
A Drosophila RNAi library modulates Hippo pathway-dependent tissue growth
Nature Communications, 2016 Drosophila RNAi libraries are commonly used to perform large-scale functional genetics screens in vivo. Here the authors find that a subset of lines from the VDRC KK RNAi line cause false-positive enhancement of the Hippo pathway, and provide a strain ...
Joseph H.A. Vissers +3 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Medication nonadherence during the first 100 days after pediatric hematopoietic stem cell transplantation (HSCT) and during oncology treatment increases risk for complications. BMT4me is a caregiver‐facing mobile health (mHealth) application providing medication reminders, symptom tracking, and note‐taking features to support ...
Micah A. Skeens +4 more
wiley +1 more source
Adolescent acne: association to sex, puberty, testosterone and dihydrotestosterone
Endocrine ConnectionsThe manifestation of acne in adolescents coincides with the emergence of other androgen-dependent characteristics of puberty such as sweat odor and pubic hair. Yet, little is known about the associations with circulating levels of androgens.
Nanna E Jakobsen +8 more
doaj +1 more source
THE GROWTH OF BACTERIOPHAGE [PDF]
Journal of General Physiology, 1939 1. An anti-Escherichia coli phage has been isolated and its behavior studied. 2. A plaque counting method for this phage is described, and shown to give a number of plaques which is proportional to the phage concentration. The number of plaques is shown to be independent of agar concentration, temperature of plate incubation, and ...
Ellis, Emory L., Delbrück, Max
openaire +3 more sources
Biotechnology & Biotechnological Equipment, 2021 Fatty acids (FAs) in oilseeds are important for human health. Gas chromatography-mass spectrometry (GC-MS) is a popular analytical technology for FAs measurement. FAs need to be derivatized into fatty acid methyl esters (FAMEs), which is essential for GC-
Shuai Xiao +5 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Hemophilic arthropathy remains the leading morbidity in hemophilia despite modern prophylaxis, and early joint damage may be missed by routine exams. This study explored T2* MRI as a noninvasive biomarker of hemosiderin deposition in pediatric hemophilia.
Jessica Garcia +6 more
wiley +1 more source
Tackling Discrepancies in Trade Data: The Harvard Growth Lab International Trade Datasets
Scientific DataBilateral trade data informs foreign and domestic policy decisions, serves as a growth indicator, determines tariffs, and is the basis for financial and investment decisions for corporations.
Sebastián Bustos +8 more
doaj +1 more source