Results 81 to 90 of about 15,107,547 (307)

RelA Inhibits Embryonic Myogenesis by Coordinately Regulating a Novel Distal Enhancer of Myogenin

Advanced Science
Skeletal muscle is crucial for lifelong metabolic health, with its development initiating during embryogenesis and guiding later growth. Single‐cell RNA sequencing of E13.5 mouse embryos suggests that maternal obesity impairs embryonic myogenesis ...
Md Nazmul Hossain, Yao Gao, Sharmeen Islam, Li‐Wei Chen, Xinrui Li, Zhongyun Kou, Nathan C Law, Jeanene Marie deAvila, Mei‐Jun Zhu, Min Du   +9 more
doaj   +1 more source

Investigating the Relationship between Nocturnal Enuresis and Sleep Disordered Breathing Using Polysomnography Data of 5-10 Year-Old Children Referred to Qazvin Children's Hospital, Iran

Journal of Sleep Sciences
Background and Objective: Sleep is a critical biological necessity essential for maintaining both physical and mental health in humans. Given the prevalence of nocturnal enuresis (NE) in children, this study sought to explore its potential link to sleep-
Shabnam Jalilolghadr, Zahra Soltantooyeh, Mehdi Alizadeh, Khatereh Khameneh Pour, Alireza Razzaghi, Atieyh Alsadat Moeeni   +5 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Investigation of the Relationship between Sleep Habits and Sleep Structure by Polysomnography in 3-10 Year-Old Children Referring to the Sleep Department of Qazvin Children's Hospital, Iran

Journal of Sleep Sciences
Background and Objective: Improper sleeping habits can affect children's sleep structure and reduce the quantity and quality of sleep. In this study, we aimed to investigate the relationship between sleep habits and sleep structure in children ...
Shabnam Jalilolghadr, Zahra Soltantooyeh, Aliraza Razzaghi, Atieyh Alsadat Moeeni, Khatereh Khameneh Pour, Zahra Mohammadi   +5 more
doaj   +1 more source

An Integrated Landscape Approach for Socially Inclusive Peatland Restoration

Journal of Wetlands Environmental Management, 2020
Successful restoration and fire prevention in peat landscapes require full rewetting and permanent revegetation for optimal water retention. The ecological and socio-economic heterogeneity of these landscapes calls for integrated approaches based on ...
Timothy Jessup, Hendrik Segah, Marcel Silvius, Grahame Applegate, Yasurum Jagau   +4 more
doaj   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Traditional and Artificial Intelligent Methods in Predicting Maxillofacial Soft Tissue Morphology After Orthognathic Surgery: A Narrative Review

International Journal of Dentistry
The soft tissue morphology after orthognathic surgery has always been difficult to predict in preoperative planning. This narrative review aims to evaluate the current prediction methods and point out the direction for future research to improve ...
Tianyi Wang, Huanhuan Chen, Guangying Song, Bing Han   +3 more
doaj   +1 more source

Implementing the New Urban Agenda in Rwanda: Nation-Wide Public Space Initiatives

Urban Planning, 2019
Rwanda, with its population of 12,600,000, growing 2.8% yearly, and significant investments in infrastructure and construction in its capital Kigali and six secondary cities identified as economic poles of growth, aims to achieve a 35% urbanisation rate ...
Ilija Gubic, Oana Baloi
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source