Results 81 to 90 of about 14,183,882 (362)

Cytosolic‐enhanced dark Epac‐based FRET sensors allow for intracellular cAMP detection in live cells via FLIM

open access: yesFEBS Letters, EarlyView.
We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti   +2 more
wiley   +1 more source

Investigation of the Relationship between Sleep Habits and Sleep Structure by Polysomnography in 3-10 Year-Old Children Referring to the Sleep Department of Qazvin Children's Hospital, Iran

open access: yesJournal of Sleep Sciences
Background and Objective: Improper sleeping habits can affect children's sleep structure and reduce the quantity and quality of sleep. In this study, we aimed to investigate the relationship between sleep habits and sleep structure in children ...
Shabnam Jalilolghadr   +5 more
doaj   +1 more source

Growth and growth hormone in the dog [PDF]

open access: yesVeterinary Quarterly, 1994
(1994). Growth and growth hormone in the dog. Veterinary Quarterly: Vol. 16, No. sup1, pp. 31-32.
R.C. Nap   +2 more
openaire   +3 more sources

Diphthamide synthesis is linked to the eEF2‐client chaperone machinery

open access: yesFEBS Letters, EarlyView.
The diphthamide modification of eukaryotic translation elongation factor 2 (eEF2) is important for accurate protein synthesis. We addressed the potential coordination of de novo eEF2 synthesis with simultaneous or subsequent diphthamide modification. Our work reveals that the co‐chaperones Hgh1 and Cpr7, which are known to support folding of nascent ...
Lars Kaduhr   +4 more
wiley   +1 more source

The [2Fe‐2S] cluster of mitochondrial outer membrane protein mitoNEET has an O2‐regulated nitric oxide access tunnel

open access: yesFEBS Letters, EarlyView.
The mitochondrial outer membrane iron–sulphur ([Fe‐S]) protein mitoNEET is a target of the type‐2 diabetes drug pioglitazone. Its unknown molecular function is linked to respiratory complex activity and mitochondrial function. We discovered that O2 protects the mitoNEET [2Fe‐2S] cluster against NO oxidation and desensitization towards reduction by H2S.
Thao Nghi Hoang   +9 more
wiley   +1 more source

Evaluation of the DWP Growth Fund [PDF]

open access: yes, 2011
The objective of the DWP Growth Fund was to raise levels of access to affordable credit by building the capacity of third sector lenders to serve financially excluded households.
Collard, Sharon   +2 more
core  

Financial conditions and the risks to economic growth in the United States since 1875 [PDF]

open access: yes, 2020
We explore the historical relationship between financial conditions and real economic growth for quarterly U.S. data from 1875 to 2017 with a flexible empirical copula modelling methodology.
Coe, Patrick, Vahey, Shaun P.
core  

Characterization of fungal carbonyl sulfide hydrolase belonging to clade D β‐carbonic anhydrase

open access: yesFEBS Letters, EarlyView.
Here, we performed a functional analysis of the fungal enzymes belonging to clade D of the β‐class carbonic anhydrase family (β‐D‐CA). The β‐D‐CAs in the basidiomycete Gloeophyllum trabeum and the ascomycete Trichoderma harzianum showed very low activity in the hydration of CO2 but exhibited high activity in the hydrolysis of carbonyl sulfide (COS ...
Ryuka Iizuka   +6 more
wiley   +1 more source

Salt-assisted vapor-liquid-solid growth of one-dimensional van der Waals materials [PDF]

open access: yesarXiv, 2023
We have combined the benefits of two catalytic growth phenomena to form nanostructures of transition metal trichalcogenides (TMTs), materials that are challenging to grow in a nanostructured form by conventional techniques, as required to exploit their exotic physics.
arxiv  

Growth in growth hormone insensitivity

open access: yesTrends in Endocrinology & Metabolism, 1994
Primary GH insensitivity due to GH receptor deficiency (GHRD) provides a model for studying the discrete effects of severe IGF-I deficiency on growth and body composition. Growth failure in utero is doubtful, but postpartum growth proceeds at rates that result in adult statures 4-12 standard deviations (SDs) below the normal mean.
The Department of Pediatrics, University of Florida College of Medicine, Gainesville, FL 32608, USA ( host institution )   +4 more
openaire   +4 more sources

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