Results 151 to 160 of about 9,677,906 (304)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Modelling population dynamics of Frankliniella occidentales Pergande (Thysanoptera: Thripidae) on greenhouse grown chrysanthemum

European Journal of Horticultural Science, 2008
M. Nothnagl, A. Kosiba, B. W. Alsanius, P. Anderson, R. U. Larsen   +4 more
doaj   +1 more source

Growth analysis of cotton using UAS derived multi temporal canopy features. [PDF]

Sci Rep
Palla S, Sarkar S, Zhao L, Landivar J, Scott JL, Maeda M, McGinty J, Abugho S, Jung J, Rajan N, Bhandari M.   +10 more
europepmc   +1 more source

Marginal structural models with latent class growth analysis of treatment trajectories: Statins for primary prevention among older adults. [PDF]

Stat Methods Med Res, 2023
Diop A, Sirois C, Guertin JR, Schnitzer ME, Candas B, Cossette B, Poirier P, Brophy J, Mésidor M, Blais C, Hamel D, Tadrous M, Lix L, Talbot D.   +13 more
europepmc   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Dry matter partitioning in a nursery and a plasticulture fruit field of strawberry cultivars 'Sweet Charlie' and 'Camarosa' as affected by prohexadione-calcium and partial leaf removal

European Journal of Horticultural Science, 2007
Y. Reekie, P. C. Struik, P. R. Hicklenton, J. R. Duval   +3 more
doaj   +1 more source

A longitudinal latent class growth analysis of PTSD symptom development in mechanically ventilated ICU patients. [PDF]

Sci Rep
Li Y, Zhang J, Wei C, Liu M, Xiong Y, Hu R, Yuan X.   +6 more
europepmc   +1 more source

Longitudinal Three-Dimensional Stereophotogrammetric Growth Analysis in Infants with Unilateral Cleft Lip and Palate from 3 to 12 Months of Age. [PDF]

J Clin Med, 2023
Kluge J, Bruggink R, Pandis N, Unkovskiy A, Jost-Brinkmann PG, Kuijpers-Jagtman AM, Bartzela T.   +6 more
europepmc   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

The haves and the have-nots: Identifying typologies of change in relative deprivation using multi-trajectory latent class growth analysis. [PDF]

Br J Soc Psychol
Lilly KJ, Sibley CG, Osborne D.
europepmc   +1 more source