Results 101 to 110 of about 11,150,175 (351)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Productivity Growth and the Phillips Curve: A Reassessment of the US Experience [PDF]

open access: yes
In this paper we analyse a new Phillips curve (NPC) model and demonstrate that (i) frictional growth, i.e. the interplay of wage-staggering and money growth, generates a nonvertical NPC in the long-run, and (ii) the Phillips curve (PC) shifts with ...
Karanassou, Marika, Sala, Hector
core   +3 more sources

Crescimento e produção de brócolis em sistema orgânico em função de doses de composto Growth and yield of broccoli on organic production system as a function of compost dosages

open access: yesCiência e Agrotecnologia, 2008
A utilização de composto orgânico na produção de olerícolas resulta em efeitos diversos e complexos. Embora seja crescente a pesquisa voltada para a produção orgânica de olerícolas, os efeitos do composto orgânico sobre o crescimento e a produção dessas ...
Ellen Rúbia Diniz   +5 more
doaj   +1 more source

From Phillips curve to wage curve [PDF]

open access: yes
In most traditional macro-economic models of the Netherlands the wage equation is specified by a Phillips curve, in which wage growth is negatively related to the unemployment rate.
Graafland, J.J.
core   +1 more source

Statistics of layered zigzags: a two-dimensional generalization of TASEP [PDF]

open access: yes, 2010
A novel discrete growth model in 2+1 dimensions is presented in three equivalent formulations: i) directed motion of zigzags on a cylinder, ii) interacting interlaced TASEP layers, and iii) growing heap over 2D substrate with a restricted minimal local ...
Borodin A   +13 more
core   +2 more sources

Economic growth and environmental pollution in West Africa: Testing the Environmental Kuznets Curve hypothesis

open access: yes, 2018
Several studies suggest that increased economic activities result in poor environmental quality while others argue otherwise, due to the demand for improved environmental quality as a result of higher incomes.
Derick T. Adu, E. Denkyirah
semanticscholar   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Influence of soft cheese technology on the growth and enterotoxin production of Staphylococcus aureus

open access: yesCzech Journal of Food Sciences, 2009
The aim of this study was to monitor S. aureus growth and toxin production in soft cheese during the technological processing. In model experiments, raw milk was inoculated separately with five S. aureus strains isolated from milk and milk products.
Lenka Necidová   +6 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Purified glycerin in balanced diets of broiler chickens treated from 1 to 42 days of age

open access: yesRevista Brasileira de Zootecnia
We evaluated the technical feasibility of purified glycerin inclusion in balanced diets of broiler chickens treated from 1 to 42 days of age. A total of 240 broiler chickens were distributed in a completely randomized design into four treatments (0, 2, 4,
Mônica Calixto da Silva   +7 more
doaj   +1 more source

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