Results 81 to 90 of about 7,518,884 (305)
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
grofit: Fitting Biological Growth Curves with R [PDF]
The grofit package was developed to fit many growth curves obtained under different conditions in order to derive a conclusive dose-response curve, for instance for a compound that potentially affects growth.
Jost Ludwig +4 more
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A utilização de composto orgânico na produção de olerícolas resulta em efeitos diversos e complexos. Embora seja crescente a pesquisa voltada para a produção orgânica de olerícolas, os efeitos do composto orgânico sobre o crescimento e a produção dessas ...
Ellen Rúbia Diniz +5 more
doaj +1 more source
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Economic growth and atmospheric pollution in Spain: discussing the environmental Kuznets curve by hypothesis [PDF]
The environmental Kuznets curve (EKC) hypothesis posits an inverted U relationship between environmental pressure and per capita income. Recent research has examined this hypothesis for different pollutants in different countries.
Vittorio Galletto +3 more
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The aim of this study was to monitor S. aureus growth and toxin production in soft cheese during the technological processing. In model experiments, raw milk was inoculated separately with five S. aureus strains isolated from milk and milk products.
Lenka Necidová +6 more
doaj +1 more source
An Interpretation of Cell Growth Curves [PDF]
It is shown that typical cell elongation curves with time, as reported in the literature, are the consequence of a very simple trend of relative elemental elongation rate with time.
openaire +2 more sources
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
An Empirical Study of the Relationships between CO2 Emissions, Economic Growth and Openness [PDF]
This paper investigates the existence of the environmental Kuznets curve (EKC) for carbon dioxide (CO2) emissions and its causal relationships with economic growth and openness by using time series data (1971-2006) from China (an emerging market), Korea (
Heshmati, Almas +2 more
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A new framework for yield curve, output and inflation relationships [PDF]
This article develops a theoretically-consistent and easy-to-apply framework for interpreting, investigating, and monitoring the relationships between the yield curve, output, and inflation.
Krippner, Leo
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