Results 61 to 70 of about 1,653,692 (278)

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Comparison of four nonlinear growth models in Creole chickens of Mexico

open access: yesPoultry Science, 2020
Animal growth is a complex and dynamic process that involves physiological and morphological changes from hatching to maturity. It is defined as the increase in body size per time unit.
Analy Mata-Estrada   +7 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Hyperbolastic type-III diffusion process: Obtaining from the generalized Weibull diffusion process

open access: yesMathematical Biosciences and Engineering, 2020
The modeling of growth phenomena has become a matter of great interest in many different fields of application and research. New stochastic models have been developed, and others have been updated to this end.
Antonio Barrera   +2 more
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Crescimento e deposição de nutrientes nas penas, músculo, ossos e pele de frangos de corte de duas linhagens comerciais Growth and nutrient deposition on feathers, muscles, bones, and skin of two broiler chicken strains

open access: yesCiência e Agrotecnologia, 2009
Conduziu-se este trabalho, com o objetivo de avaliar o perfil de crescimento e de deposição de nutrientes nas penas, nos músculos, nos ossos e na pele de machos e fêmeas de frangos de corte das linhagens Ross e Cobb, no período de 1 a 56 dias de idade ...
Simara Márcia Marcato   +5 more
doaj   +1 more source

A simple spreadsheet model to incorporate seasonal growth into length-based stock assessment methods [PDF]

open access: yes, 2006
The paper describes a method by which seasonal growth can be incorporated into length-converted catch curves and cohort analyses using a spreadsheet. The method is based on calculating the length of fish using seasonal growth parameters on a daily basis.
de Graaf, G.J., Dekker, P.
core  

Mirzakhani's Curve Counting: From Simple to All

open access: yes, 2022
Mirzakhani obtained the asymptotic growth, when $L\to\infty$, of the number of curves in the mapping class group orbit of some given simple curve and with length at most $L$. Years later she extended this result from simple to arbitrary curves.
Erlandsson, Viveka, Souto, Juan
core  

Growth standard charts for monitoring bodyweight in dogs of different sizes [PDF]

open access: yes, 2017
Limited information is available on what constitutes optimal growth in dogs. The primary aim of this study was to develop evidence-based growth standards for dogs, using retrospective analysis of bodyweight and age data from >6 million young dogs ...
Butterwick, RF   +6 more
core   +3 more sources

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

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