Results 161 to 170 of about 18,735,403 (324)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Capturing infant and child growth dynamics with P-splines mixed effects models. [PDF]

Int J Obes (Lond)
Hernandez MA, Li Z, Cole TJ, Ong YY, Tilling K, Elhakeem A.   +5 more
europepmc   +2 more sources

Temperature regulation of cell cycle and growth dynamics in Arabidopsis. [PDF]

Biochem Soc Trans
Sundaravadivelu V, Raipuria RK, Ranjan A.   +2 more
europepmc   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Cholesterol granuloma of the sphenoid wing with long-term growth dynamics: illustrative case. [PDF]

J Neurosurg Case Lessons
Hirano Y, Kinoshita M, Tamai S, Tanaka S, Misaki K, Ikeda H, Nakada M.   +6 more
europepmc   +1 more source

Genetic variation of growth dynamics in maize (Zea mays L.) revealed through automated non‐invasive phenotyping

The Plant Journal, 2017
M. Muraya, Jianting Chu, Yu-Sheng Zhao, A. Junker, Christian Klukas, J. Reif, T. Altmann   +6 more
semanticscholar   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Transitional dynamics in R&D-based models of endogenous growth [PDF]

This paper offers a comprehensive study on transitional dynamics within R&D-based models of endogenous growth. There are two main motivations. First, the complete dynamic system for the market solution is derived in general form.
Steger, Thomas M.
core  

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Analysing Growth and Distribution Dynamics - Isolating Divergence Factors [PDF]

This paper analyses the factors driving convergence and divergence processes in the growth dynamics of European urban regions over the period 1978 to 1994. To achieve this, we develop a two-stage procedure. First, viewing growth of real GDP per capita as
Paul Cheshire, Stefano Magrini
core