Results 171 to 180 of about 852,362 (315)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

dAMN: a genome-scale neural-mechanistic hybrid model to predict bacterial growth dynamics. [PDF]

Bioinformatics
Faulon JL, Dursoniah D, Ahavi P, Raynal A, Asin-Garcia E.   +4 more
europepmc   +1 more source

Changing technology trends, transition dynamics and growth accounting [PDF]

The technology growth trends that underlie recent productivity patterns are investigated in a framework that incorporates investment-specific technological progress.
Michael R. Pakko
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

KymoTip: high-throughput characterization of tip-growth dynamics in plant cells. [PDF]

Plant J
Kang Z, Kimata Y, Nonoyama T, Ikeuchi T, Kuchitsu K, Tsugawa S, Ueda M.   +6 more
europepmc   +1 more source

The dynamics of a two‐ class growth model with optimal saving and switch in behavior

, 2019
We present a two-class economy where capitalists and workers live two periods. Workers may change their saving behaviour depending on their level of wealth.
Commendatore p
core  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Auxin and cytokinin regulate growth dynamics underlying carpel initiation in Arabidopsis. [PDF]

J Exp Bot
Gómez-Felipe A, de Folter S, Kierzkowski D.   +2 more
europepmc   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Growth dynamics of 3,909 Escherichia coli single-gene knockouts in rich and minimal media. [PDF]

Sci Data
Lao Z, Ying BW.
europepmc   +1 more source