Results 171 to 180 of about 905,382 (336)

The restoration of cardiac hypertrophy and blood pressure in hypophysectomized rats by large doses of lyophilized anterior pituitary and growth hormone [PDF]

, 1954
Margaret Beznák
openalex   +1 more source

Synthetic Lethality of SHP2 and XIAP Suppresses Proliferation and Metastasis in KRAS‐mutant Nonsmall Cell Lung Cancer

Advanced Science, EarlyView.
Embelin cotargets SHP2 to disrupt the SHP2/GRB2/SOS complex, inhibiting cancer‐related signaling pathways such as MAPK, (PI3K)/AKT pathway, and XIAP to induce apoptosis signaling pathway, respectively, leading to synthetic lethality in KRAS‐mutant NSCLC cells both in vivo and in vitro.
Nai‐jie Fu, Yu‐wen Sheng, Zhe Fan, Zhao Wu, Ling‐yu Li, Rui‐ying Xi, Xiao‐ke Shi, Guo‐lin Zhang, Fei Wang   +8 more
wiley   +1 more source

Effects of Growth Hormone in Vitro on the Metabolism of Glucose in Rat Adipose Tissue

, 1959
Albert I. Winegrad, Walter N. Shaw, F. D. W. Lukens, William Stadie, Albert E. Renold   +4 more
openalex   +1 more source

Growth hormone therapy for growth hormone deficiency

, 2012
published_or_final_version ; Medical Sciences ; Master ; Master of Medical ...
openaire   +3 more sources

Coordinated Role of Autophagy and ERAD in Maintaining Neuroendocrine Function by Preventing Prohormone Aggregation

Advanced Science, EarlyView.
By studying the maturation mechanisms of vasopressin (AVP), this manuscript identifies FAM134B‐mediated ER‐phagy as a critical pathway for degrading both aggregated proAVP and the key ERAD component, HRD1. HRD1 induction mitigates proAVP aggregation and support AVP neuron function in the absence of autophagy.
Xuya Pan, Xing He, Su Wu, Na Xiong, Xinyu Hou, Heting Wang, Diane Somlo, Martin Spiess, Haiyang Wang, Jifeng Yang, Chunliang Li, Shasha Li, Wenbin Ma, Yanming Chen, Jun Cui, Ling Qi, Guojun Shi   +16 more
wiley   +1 more source

A NEW PREPARATION OF CRYSTALLINE ANTERIOR PITUITARY GROWTH HORMONE

, 1948
Alfred E. Wilhelmi, Jacob B. Fishman, Jane A. Russell   +2 more
openalex   +1 more source

The effect of pituitary growth hormone and of insulin on the level of oxidized and reduced coenzyme I in the livers of normal and diabetic rats [PDF]

, 1956
A. L. Greenbaum, Clive N. Graymore
openalex   +1 more source

Enhancer Profiling Reveals a Protective Role of RXRα Against Calcium Oxalate‐Induced Crystal Deposition and Kidney Injury

Advanced Science, EarlyView.
Comprehensive epigenomic and transcriptomic profiling revealed a dynamic enhancer landscape and gene expression program associated with nephrolithiasis, highlighting RXRα as a central transcription factor in this regulatory network. Tubular‐specific deletion of RXRα increased intrarenal CaOx crystal deposition, while its activation with Bexarotene ...
Yu Yang, Xudan Dou, Yongzhan Sun, Mengyao Wang, Jing Wang, Xinyi Cao, Haijie Xie, Linguo Xie, Weiping Tian, Jing Nie, Yupeng Chen, Chunyu Liu, Lirong Zhang   +12 more
wiley   +1 more source

THE EFFECT OF GROWTH HORMONE ON LIPOGENESIS IN INTACT AND ADRENALECTOMIZED RATS [PDF]

, 1955
W. F. Perry, Helen F. Bowen
openalex   +1 more source

N4‐Acetylcytidine‐Mediated CD2BP2‐DT Drives YBX1 Phase Separation to Stabilize CDK1 and Promote Breast Cancer Progression

Advanced Science, EarlyView.
The long non‐coding RNA (lncRNA) CD2BP2‐DT is upregulated in breast cancer and correlates with poor patient prognosis. Mechanistically, CD2BP2‐DT drives YBX1 phase separation to stabilize CDK1 and promote breast cancer progression. Moreover, NAT10‐mediated N4‐acetylcytosine (ac4C) modification further enhances CD2BP2‐DT expression.
Hongyu Wang, Bozhi Zhao, Jiayu Zhang, Qunyu Hu, Linlin Zhou, Yinghui Zhang, Yixin Cai, Yuansong Qu, Tao Jiang, Dongwei Zhang   +9 more
wiley   +1 more source