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Reviews in Endocrine and Metabolic Disorders, 1998
Growth hormone (GH) actions impact growth, metabolism, and body composition and have been associated with aging and longevity. Lack of GH results in slower growth, delayed maturation, and reduced body size and can lead to delayed aging, increased healthspan, and a remarkable extension of longevity.
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Growth hormone (GH) actions impact growth, metabolism, and body composition and have been associated with aging and longevity. Lack of GH results in slower growth, delayed maturation, and reduced body size and can lead to delayed aging, increased healthspan, and a remarkable extension of longevity.
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Growth hormone response to growth hormone-releasing hormone in schizophrenic patients
American Journal of Psychiatry, 1990Ten schizophrenic patients and five normal control subjects were challenged with growth hormone-releasing hormone in a pilot study investigating growth hormone secretion from the pituitary. The results suggest suprapituitary dysfunction in schizophrenia, but replication in a larger study is needed.
J.A. Lieberman +4 more
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Growth and growth hormone: An overview
Growth Hormone & IGF Research, 2016Growth is a good indicator of a child's health. Growth disturbances, including short stature or growth failure, could be indications of illnesses such as chronic disease, nutritional deficits, celiac disease or hormonal abnormalities. Therefore, a careful assessment of the various requirements for normal growth needs to be done by history, physical ...
Robert Rapaport +2 more
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Growth hormone replacement for adult growth hormone deficiency
Expert Opinion on Pharmacotherapy, 2003Growth hormone deficiency (GHD) in childhood causes growth retardation, short stature and significant impairment of adult height. Growth hormone (GH) has been given successfully to these children for > 40 years but only since the introduction of recombinant DNA technology, has enough GH been available for paediatric needs and also for other indications.
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Extrapituitary growth hormone and growth?
General and Comparative Endocrinology, 2014While growth hormone (GH) is obligatory for postnatal growth, it is not required for a number of growth-without-GH syndromes, such as early embryonic or fetal growth. Instead, these syndromes are thought to be dependent upon local growth factors, rather than pituitary GH.
Harvey, Steve, Baudet, Marie-Laure
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Growth Hormone and Cell Growth
2012Growth hormone (GH) promotes stem cell activation, cell proliferation, differentiation and survival, either directly or through the induction of IGF-1. GH acts via its cell membrane receptor to initiate a range of signalling pathways, with JAK2 kinase activation of STAT5 being the most important. The transcription factor STAT5 acts to induce expression
Andrew J. Brooks, Michael J. Waters
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2016
Growth hormone is a member of the GH/PRL/SL family produced by the anterior pituitary in all vertebrates. GH is a single-chain polypeptide containing two highly conserved intramolecular disulfide bonds that are important for biological activity. The actions of GH are initiated by its binding to a membrane-bound GHR that is located in various tissues ...
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Growth hormone is a member of the GH/PRL/SL family produced by the anterior pituitary in all vertebrates. GH is a single-chain polypeptide containing two highly conserved intramolecular disulfide bonds that are important for biological activity. The actions of GH are initiated by its binding to a membrane-bound GHR that is located in various tissues ...
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Growth Hormone & IGF Research, 1999
Although the age-related decline in serum levels of growth hormone (GH) is well documented, l,2 the possible role of GH in the control of ageing is controversial. GHreleasing peptides (GHRPs) act at both the pituitary and the hypothalamic level, where specific receptors have been located.
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Although the age-related decline in serum levels of growth hormone (GH) is well documented, l,2 the possible role of GH in the control of ageing is controversial. GHreleasing peptides (GHRPs) act at both the pituitary and the hypothalamic level, where specific receptors have been located.
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Growth hormone and growth hormone releasing hormone
1989C. G. D. Brook +10 more
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