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Growth hormone replacement for adult growth hormone deficiency
Expert Opinion on Pharmacotherapy, 2003Growth hormone deficiency (GHD) in childhood causes growth retardation, short stature and significant impairment of adult height. Growth hormone (GH) has been given successfully to these children for > 40 years but only since the introduction of recombinant DNA technology, has enough GH been available for paediatric needs and also for other indications.
Ilan Shimon
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Treatment with Growth Hormone for Adults with Growth Hormone Deficiency Syndrome: Benefits and Risks
International Journal of Molecular Sciences, 2018 Pharmacological treatment of growth hormone deficiency (GHD) in adults began in clinical practice more than 20 years ago. Since then, a great volume of experience has been accumulated on its effects on the symptoms and biochemical alterations that ...
Juan J Diez +2 more
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Progression from isolated growth hormone deficiency to combined pituitary hormone deficiency
Growth Hormone and IGF Research, 2017 Mehul T Dattani
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Dosing of Growth Hormone in Growth Hormone Deficiency
Hormone Research in Paediatrics, 1999Growth hormone (GH) treatment of GH-deficient (GHD) children is to a certain extent standardized worldwide. Recombinant 22 kDa GH is injected once daily by the subcutaneous route, mostly in the evening. The amount of GH injected (calculated per kg body weight or body surface area, expressed in terms of IU or mg) in prepubertal children mimics the known
M B, Ranke +3 more
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Diagnosis of growth hormone deficiency in the paediatric and transitional age
Best Practice and Research in Clinical Endocrinology and Metabolism, 2016Patrick Murray
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Pathogenesis and Diagnosis of Growth Hormone Deficiency in Adults.
New England Journal of Medicine, 2019Growth Hormone Assessment in Adults Growth hormone synthesis and physiology are discussed in the context of recombinant growth hormone use in adults.
S. Melmed
semanticscholar +1 more source
Growth hormone deficiency in the adult
Pituitary, 2006Growth hormone deficiency (GHD) in adults may be of either adult or childhood onset and may occur as isolated GHD or as multiple hormone deficiencies. Adult-onset GHD (AoGHD) usually results from damage to the pituitary gland or hypothalamus. GH is frequently undetectable in normal subjects and thus GHD cannot be distinguished from the normal state ...
DOGA M +4 more
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Growth hormone deficiency in children
Pituitary, 2008The foundation for the diagnosis of growth hormone (GH) deficiency in childhood must be auxology, that is, the comparison of the child's growth pattern to that of established norms for gender and ethnicity. It is only in those growing considerably more slowly than average that testing for GHD makes sense. Assessment of laboratory tests, whether static,
Erick J, Richmond, Alan D, Rogol
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A review of growth hormone deficiency
Paediatrics & child health, 2019Growth hormone deficiency (GHD) is a rare but important cause of short stature in children. It is treatable. However, diagnosis is challenging and often requires referral to a specialist paediatric endocrinologist to facilitate testing and the ...
M. Dattani, N. Malhotra
semanticscholar +1 more source