Results 21 to 30 of about 486,283 (378)
Oman Medical Journal, 2017 Objectives: The use of growth hormone (GH) in idiopathic short stature (ISS) has been a subject of debate for the past two decades. We sought to assess the effect of GH on final height (FH) in patients with ISS in our region, which has a high ...
Shireen Mreish +2 more
doaj +1 more source
Endocrine Practice, 2019 Objective: The development of these guidelines is sponsored by the American Association of Clinical Endocrinologists (AACE) Board of Directors and American College of Endocrinology (ACE) Board of Trustees and adheres with published AACE protocols for the
K. Yuen +6 more
semanticscholar +1 more source
Treatment with Growth Hormone for Adults with Growth Hormone Deficiency Syndrome: Benefits and Risks
International Journal of Molecular Sciences, 2018 Pharmacological treatment of growth hormone deficiency (GHD) in adults began in clinical practice more than 20 years ago. Since then, a great volume of experience has been accumulated on its effects on the symptoms and biochemical alterations that ...
J. Díez +2 more
semanticscholar +1 more source
Unbinding of Retinoic Acid from its Receptor Studied by Steered Molecular Dynamics [PDF]
Biophysical Journal 76, 188 (1999), 1999 Retinoic acid receptor (RAR) is a ligand-dependent transcription factor that regulates the expression of genes involved in cell growth, differentiation, and development. Binding of the retinoic acid hormone to RAR is accompanied by conformational changes in the protein which induce transactivation or transrepression of the target genes.
arxiv +1 more source
Growth Hormone Deficiency Following Traumatic Brain Injury
International Journal of Molecular Sciences, 2019 Traumatic brain injury (TBI) is fairly common and annually affects millions of people worldwide. Post traumatic hypopituitarism (PTHP) has been increasingly recognized as an important and prevalent clinical entity.
O. Kgosidialwa +3 more
semanticscholar +1 more source
Growth Hormone Deficiency: Health and Longevity.
Endocrine reviews, 2018 The important role of GH in the control of mammalian longevity was first deduced from extended longevity of mice with genetic GH deficiency (GHD) or GH resistance.
M. Aguiar-Oliveira, A. Bartke
semanticscholar +1 more source
Diagnosis and Treatment of Hypopituitarism [PDF]
Endocrinology and Metabolism, 2015 Hypopituitarism is a chronic endocrine illness that caused by varied etiologies. Clinical manifestations of hypopituitarism are variable, often insidious in onset and dependent on the degree and severity of hormone deficiency.
Seong Yeon Kim
doaj +1 more source
PLoS ONE, 2018 Background Quantifying the association between adherence and the growth response to growth hormone (GH) treatment is hampered by suboptimal methods of measuring adherence, confounders associated with the growth response, and restriction of the outcome ...
P. van Dommelen, E. Koledova, J. Wit
semanticscholar +1 more source
Mìžnarodnij Endokrinologìčnij Žurnal, 2019 Background. According to world statistics, about 5–10 % of newborns are small for gestational age (SGA). They can have inadequate rates of postnatal growth during first two years of life.
O.V. Bolshova, N.M. Muz
doaj +1 more source
High Sensitivity Mass Spectrometric Quantification of Serum Growth Hormone by Amphiphilic Peptide Conjugation [PDF]
J Mass Spectrom 47(2012)1554, 2012 Amphiphilic peptide conjugation affords a significant increase in sensitivity with protein quantification by electrospray-ionization mass spectrometry. This has been demonstrated here for human growth hormone in serum using N-(3-iodopropyl)-N,N,N-dimethyloctylammonium iodide (IPDOA-iodide) as derivatizing reagent.
arxiv +1 more source