Results 11 to 20 of about 280,040 (307)

TREATMENT OF GROWTH-HORMONE DEFICIENCY WITH GROWTH-HORMONE-RELEASING HORMONE

The Lancet, 1987
18 prepubertal growth-hormone (GH)-deficient children were treated with twice-daily subcutaneous injections of a growth-hormone-releasing hormone analogue, GHRH (1-29) NH2. In 12 of the children the height velocity rose on GHRH treatment, and 8 were judged to have shown a worthwhile response to therapy in that their height velocities during the first 6
Ross, R.J.M., Tsagarakis, S., Grossman, A., Preece, M.A., Rodda, C., Davies, P.S.W., Rees, L.H., Savage, M.O., Besser, G.M.   +8 more
openaire   +5 more sources

Prolyl Endopeptidase-like Deficiency Associated with Growth Hormone Deficiency

JCRPE, 2023
Prolyl endopeptidase-like (PREPL) deficiency (MIM#616224) is a rare congenital disorder characterised by neonatal hypotonia and feeding difficulties, growth hormone (GH) deficiency and hypergonadotropic hypogonadism.
Laura Sayol-Torres, Maria Irene Valenzuela, Rosangela Tomasini, Paula Fernández-Alvarez, Maria Clemente, Diego Yeste   +5 more
doaj   +1 more source

Defective minor spliceosome mRNA processing results in isolated familial growth hormone deficiency [PDF]

, 2014
The molecular basis of a significant number of cases of isolated growth hormone deficiency remains unknown. We describe three sisters affected with severe isolated growth hormone deficiency and pituitary hypoplasia caused by biallelic mutations in the ...
Ali Oghabian, Armand Gutiérrez‐Arumí, Bhupendra Verma, Gabriel Á Martos‐Moreno, Ivon Cuscó, Jesús Argente, Julie A Chowen, Luis A Pérez‐Jurado, Mikko J Frilander, Pfäffle R, Pérez Jurado LA, Raquel Flores   +11 more
core   +2 more sources

Evaluation of cases with growth hormone deficiency

Acta Medica Alanya, 2019
Aim:The purpose of this study was to elicit data concerning the clinical and laboratory features of children with growth hormone deficiency monitored by the Pediatric Endocrinology and Metabolism Polyclinic in order to produce useful information for ...
Meltem Di̇rek, Ceyhun Di̇zdarer, Türkan Günay, İlker Günay   +3 more
doaj   +1 more source

A female survivor of childhood medulloblastoma presenting with growth-hormone-induced edema and inflammatory lesions: a case report [PDF]

, 2009
Introduction The improved survival of children with brain tumors has increased concerns about treatment-related sequelae. Growth hormone deficiency is frequently observed after craniospinal irradiation for medulloblastoma.
Veronica Biassoni, Federica Pallotti, Filippo Spreafico, Ettore Seregni, Lorenza Gandola, Antonella Martinetti, Emilio Bombardieri, Maura Massimino   +7 more
core   +1 more source

Cushing disease due to a somatic USP8 mutation in a patient with evolving pituitary hormone deficiencies due to a germline GH1 splicing variant

Archives of Endocrinology and Metabolism, 2022
SUMMARY We present the unique case of an adult Brazilian woman with severe short stature due to growth hormone deficiency with a heterozygous G to T substitution in the donor splice site of intron 3 of the growth hormone 1 (GH1) gene (c.291+1G>T).
Julia Haddad Labello, Anna Flávia Figueredo Benedetti, Bruna Viscardi Azevedo, Alexander Augusto de Lima Jorge, Valter Angelo Sperling Cescato, Sergio Rosemberg, Fernando Pereira Frasseto, Ivo Jorge Prado Arnhold, Luciani Renata Silveira de Carvalho   +8 more
doaj   +1 more source

Consensus guidelines for the diagnosis and treatment of adults with growth hormone deficiency: Summary statement of the growth hormone research society workshop on adult growth hormone deficiency [PDF]

, 1998
Based on the increasing body of evidence that adults with GH deficiency (somatotropin deficiency) have impaired health that improves with GH replacement, many countries have already approved the use of GH for replacement therapy in adults with GH ...
Clemmons, David, Growth Hormone Research Society Workshop on Adult Growth Hormone Deficiency   +1 more
core   +2 more sources

Harmonization of growth hormone measurements with different immunoassays by data adjustment [PDF]

, 2011
Background: The aim of our study was to evaluate the between-assay variability of commercially available immunoassays for the measurement of human growth hormone (hGH).
Bidlingmaier, Martin, Binder, Gerhard, Blankenstein, Oliver, Heider, Annegret, Kiess, Wieland, Kratzsch, Jürgen, Körner, Antje, Müller, Anne, Pfäffle, Roland, Scholz, Markus, Thiery, Joachim   +10 more
core   +1 more source

Growth Hormone Deficiency in the Transition Period

Endocrinology Research and Practice, 2019
The importance of continuing growth hormone therapy in the transition and adulthood periods must be studied in adolescents with growth hormone deficiency with childhood onset.
Doğuş VURALLI
doaj   +1 more source

Anophthalmia, hearing loss, abnormal pituitary development and response to growth hormone therapy in three children with microdeletions of 14q22q23 [PDF]

, 2014
BACKGROUND: Microdeletions of 14q22q23 have been associated with eye abnormalities and pituitary defects. Other phenotypic features in deletion carriers including hearing loss and response to growth hormone therapy are less well recognized.
Audrey Briand-Suleau, Corinne Metay, Elsa Zemankova, Gerard Tachdjian, Jan Lebl, Karen Milcent, Lucie Tosca, Martina Simandlova, Michel Goossens, Petra Dusatkova, Philippe Labrune, Sophie Brisset, Zdenek Sedlacek, Zdenek Sumnik, Zuzana Slamova   +14 more
core   +3 more sources