Results 21 to 30 of about 513,834 (341)

Similar safety and efficacy in previously treated adults with growth hormone deficiency randomized to once‐weekly somapacitan or daily growth hormone

Clinical Endocrinology, 2020
Somapacitan is a long‐acting, reversible albumin‐binding growth hormone (GH) derivative in development. This study aimed to evaluate the safety and efficacy of once‐weekly somapacitan versus daily GH over 52 weeks in Japanese patients with adult growth ...
F. Otsuka, Yutaka Takahashi, S. Tahara, Y. Ogawa, M. H. Rasmussen, K. Takano   +5 more
semanticscholar   +1 more source

Effect of growth hormone therapy on Taiwanese children with growth hormone deficiency

Journal of the Formosan Medical Association, 2012
Human growth hormone (GH) has been successfully used in children with GH deficiency (GHD). However, there are few published data on the effect of GH in Taiwanese children with GHD.
Ying-Hua Huang, Yau-Yau Wai, Yang-Hau Van, Fu-Sung Lo   +3 more
doaj   +1 more source

Expanding the phenotype of biallelic RNPC3 variants associated with growth hormone deficiency

American Journal of Medical Genetics. Part A, 2020
Pathogenic variants in components of the minor spliceosome have been associated with several human diseases. Recently, it was reported that biallelic RNPC3 variants lead to severe isolated growth hormone deficiency and pituitary hypoplasia.
Eline A. Verberne, Sonja Faries, M. Mannens, A. Postma, M. V. van Haelst   +4 more
semanticscholar   +1 more source

Cushing disease due to a somatic USP8 mutation in a patient with evolving pituitary hormone deficiencies due to a germline GH1 splicing variant

Archives of Endocrinology and Metabolism, 2022
SUMMARY We present the unique case of an adult Brazilian woman with severe short stature due to growth hormone deficiency with a heterozygous G to T substitution in the donor splice site of intron 3 of the growth hormone 1 (GH1) gene (c.291+1G>T).
Julia Haddad Labello, Anna Flávia Figueredo Benedetti, Bruna Viscardi Azevedo, Alexander Augusto de Lima Jorge, Valter Angelo Sperling Cescato, Sergio Rosemberg, Fernando Pereira Frasseto, Ivo Jorge Prado Arnhold, Luciani Renata Silveira de Carvalho   +8 more
doaj   +1 more source

Harmonization of growth hormone measurements with different immunoassays by data adjustment [PDF]

, 2011
Background: The aim of our study was to evaluate the between-assay variability of commercially available immunoassays for the measurement of human growth hormone (hGH).
Bidlingmaier, Martin, Oliver Blankenstein, Jürgen Kratzsch, Körner, Antje, Wieland Kiess, Anne Müller, Markus Scholz, Antje Körner, Thiery, Joachim, Martin Bidlingmaier, Müller, Anne, Scholz, Markus, Blankenstein, Oliver, Annegret Heider, Roland Pfäffle, Joachim Thiery, Heider, Annegret, Kratzsch, Jürgen, Gerhard Binder, Pfäffle, Roland, Binder, Gerhard, Kiess, Wieland   +21 more
core   +1 more source

The influence of growth hormone deficiency on bone health and metabolism

, 2023
Growth hormone (GH) is a key peptide hormone in the regulation of bone metabolism, through its systemic and paracrine action mediated directly as well as by insulin-like growth factor-1 (IGF-1).
Jakub Wydra, Wojciech Zgliczyński, Arnika Wydra, Izabella Czajka-Oraniec   +3 more
core   +1 more source

Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation [PDF]

, 2010
Study found that treatment with recombinant human growth hormone gave significantly greater benefits in stature for children with growth hormone deficiency (GHD), Turner syndrome, Prader–Willi syndrome, chronic renal insufficency, short stature homeobox ...
Bird, A., Baxter, L, Gospodarevskaya, E., K Welch, Cooper, Keith, L Baxter, Frampton, G. K., A Bird, Frampton, GK, Gospodarevskaya, Elena, Gospodarevskaya, E, Welch, K, Bryant, J, Takeda, A, Frampton, G.K., Cooper, K., GK Frampton, Takeda, Andrea, Bird, A, Bryant, J., J Bryant, K Cooper, Welch, Karen, Welch, K., Baxter, L., Takeda, A., Bryant, Jackie, A Takeda, E Gospodarevskaya, Cooper, K   +29 more
core   +1 more source

TREATMENT OF GROWTH-HORMONE DEFICIENCY WITH GROWTH-HORMONE-RELEASING HORMONE

The Lancet, 1987
18 prepubertal growth-hormone (GH)-deficient children were treated with twice-daily subcutaneous injections of a growth-hormone-releasing hormone analogue, GHRH (1-29) NH2. In 12 of the children the height velocity rose on GHRH treatment, and 8 were judged to have shown a worthwhile response to therapy in that their height velocities during the first 6
Ross, R.J.M., Tsagarakis, S., Grossman, A., Preece, M.A., Rodda, C., Davies, P.S.W., Rees, L.H., Savage, M.O., Besser, G.M.   +8 more
openaire   +5 more sources

Guidelines for Growth Hormone and Insulin-Like Growth Factor-I Treatment in Children and Adolescents: Growth Hormone Deficiency, Idiopathic Short Stature, and Primary Insulin-Like Growth Factor-I Deficiency

Hormone Research in Paediatrics, 2016
Background/Aims: On behalf of the Drug and Therapeutics, and Ethics Committees of the Pediatric Endocrine Society, we sought to update the guidelines published in 2003 on the use of growth hormone (GH).
A. Grimberg, S. DiVall, C. Polychronakos, D. Allen, L. Cohen, J. B. Quintos, W. Rossi, C. Feudtner, M. Murad   +8 more
semanticscholar   +1 more source

Laron syndrome: An experience of treatment of two cases

Journal of Clinical and Translational Endocrinology Case Reports, 2021
Laron syndrome or growth hormone insensitivity is a rare disease presenting with severe postnatal growth failure. Clinically, in most circumstances, it is indistinguishable from growth hormone deficiency.
Hiya Boro, Sk Hammadur Rahman, Saurav Khatiwada, Sarah Alam, Rajesh Khadgawat   +4 more
doaj   +1 more source