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Serum afamin and its implications in adult growth hormone deficiency: a prospective GH-withdrawal study [PDF]

open access: yesFrontiers in Endocrinology
IntroductionAdult growth hormone deficiency (AGHD) is associated with a high prevalence of metabolic syndrome (MS), which contributes to the unfavorable cardiovascular risk profile in these patients.
Balázs Ratku   +18 more
doaj   +4 more sources

Guidance for the treatment of adult growth hormone deficiency with somapacitan, a long-acting growth hormone preparation [PDF]

open access: yesFrontiers in Endocrinology, 2022
Adult growth hormone deficiency (AGHD) is a rare endocrine disorder characterized by an abnormal body composition, metabolic abnormalities associated with increased cardiovascular diseases, bone loss, and impaired quality of life.
Martin Bidlingmaier   +6 more
doaj   +2 more sources

Unusual cause of post-bariatric non-insulin-mediated hypoglycemia due to adult growth hormone deficiency [PDF]

open access: yesEndocrinology, Diabetes & Metabolism Case Reports
We report a 26-year-old woman, five years after sleeve gastrectomy, who presented with a two-year history of recurrent postprandial hypoglycemia. During symptomatic episodes (blood glucose as low as 37 mg/dL), she experienced adrenergic symptoms (tremors,
Alhussain M Hakami   +4 more
doaj   +2 more sources

Potential impacts of adult growth hormone deficiency: a population-based study in England [PDF]

open access: yesBMJ Open
Objectives To investigate the potential long-term impacts of adult growth hormone deficiency (GHD).Design Observational, retrospective matched cohort.Setting UK Clinical Practice Research Datalink (CPRD) Aurum database of primary care records with ...
Marzieh Araghi   +4 more
doaj   +2 more sources

Impact of Long-Term Growth Hormone Replacement Therapy on Metabolic and Cardiovascular Parameters in Adult Growth Hormone Deficiency: Comparison Between Adult and Elderly Patients [PDF]

open access: yesFrontiers in Endocrinology, 2021
Growth hormone deficiency (GHD) in adults is due to a reduced growth hormone (GH) secretion by the anterior pituitary gland which leads to a well-known syndrome characterized by decreased cognitive function and quality of life (QoL), decreased bone ...
Elisabetta Scarano   +8 more
doaj   +2 more sources

Adult growth hormone deficiency – benefits, side effects, and risks of growth hormone replacement

open access: yesFrontiers in Endocrinology, 2013
Deficiency of growth hormone (GH) in adults results in a syndrome characterized by decreased muscle mass and exercise capacity, increased visceral fat, impaired quality of life, unfavorable alterations in lipid profile and markers of cardiovascular risk,
Mary Lim Reed   +2 more
doaj   +3 more sources

Alterations in Cortical Thickness in Young Male Patients With Childhood-Onset Adult Growth Hormone Deficiency: A Morphometric MRI Study [PDF]

open access: yesFrontiers in Neuroscience, 2019
BackgroundThe growth hormone (GH)/insulin-like growth factor-1 (IGF-1) axis plays an important role in brain structure and maintenance of brain function.
Hongbo Yang   +11 more
doaj   +2 more sources

Corrigendum: Guidance for the treatment of adult growth hormone deficiency with somapacitan, a long-acting growth hormone preparation [PDF]

open access: yesFrontiers in Endocrinology, 2023
Martin Bidlingmaier   +6 more
doaj   +2 more sources

Adult Growth Hormone Deficiency: Diagnostic and Treatment Journeys From the Patients' Perspective. [PDF]

open access: yesJ Endocr Soc, 2022
Hoffman AR   +5 more
europepmc   +2 more sources

Cushing disease due to a somatic USP8 mutation in a patient with evolving pituitary hormone deficiencies due to a germline GH1 splicing variant

open access: yesArchives of Endocrinology and Metabolism, 2022
SUMMARY We present the unique case of an adult Brazilian woman with severe short stature due to growth hormone deficiency with a heterozygous G to T substitution in the donor splice site of intron 3 of the growth hormone 1 (GH1) gene (c.291+1G>T).
Julia Haddad Labello   +8 more
doaj   +1 more source

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