New directions in growth hormone treatment in children [PDF]
Pediatric Endocrinology, Diabetes and MetabolismThis paper reviews clinical-trial evidence on the use of long-acting growth hormone (LAGH) preparations in children. Three LAGH products have been approved in Europe and the United States for paediatric growth hormone deficiency (GHD): lonapegsomatropin,
Renata Stawerska
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Growth hormone treatment in non-growth hormone-deficient children [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2014 Until 1985 growth hormone (GH) was obtained from pituitary extracts, and was available in limited amounts only to treat severe growth hormone deficiency (GHD).
Sandro Loche +3 more
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The effects of Growth hormone treatment discontinuation in Adults on Metabolic profile, Body composition and quality Of Life (GAMBOL Study) [version 1; peer review: 1 approved, 2 approved with reservations] [PDF]
NIHR Open ResearchBackground In adults, treatment of growth hormone deficiency with daily recombinant human growth hormone injections has shown to improve many clinical features associated with GHD.
Niki Karavitaki +2 more
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Final adult height in Korean children with idiopathic growth hormone deficiency after growth hormone treatment [PDF]
Scientific ReportsThis study evaluated final adult height (FAH) outcomes and associated predictive factors in patients with idiopathic growth hormone deficiency (IGHD) treated with recombinant human growth hormone (GH).
Min Hyung Cho +4 more
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Noonan Syndrome, Cancer Risk, and Growth Hormone Treatment [PDF]
JCRPECancer may occur in patients with Noonan syndrome (NS). Review of English literature revealed that myeloproliferative diseases are the most prevalent, followed by intracranial tumours.
Korcan Demir, Kübra Yüksek Acınıklı
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The rationale and design of TransCon Growth Hormone for the treatment of growth hormone deficiency [PDF]
Endocrine Connections, 2017 The fundamental challenge of developing a long-acting growth hormone (LAGH) is to create a more convenient growth hormone (GH) dosing profile while retaining the excellent safety, efficacy and tolerability of daily GH.
Kennett Sprogøe +3 more
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Growth hormone treatment and risk of malignancy [PDF]
Korean Journal of Pediatrics, 2015 Growth hormone (GH) treatment has been increasingly widely used for children with GH deficiencies as the survival rate of pediatric patients with malignancies has increased.
Hyun-Wook Chae +2 more
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Short-term effect of growth hormone treatment in childhood leukemia survivors with growth hormone deficiency [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2022 Purpose Survivors of childhood leukemia are at risk of growth impairment due to intensive chemotherapy and radiation treatments. This study investigated the auxological and biochemical characteristics of childhood leukemia survivors diagnosed with growth
Chungwoo Shin +8 more
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Molecular Basis for Hypochondroplasia in Japan
Endocrines, 2022 Hypochondroplasia is an autosomal dominant genetic disorder due to a heterozygous pathogenic variant of the FGFR3 gene. The early diagnosis of hypochondroplasia is necessary, since growth hormone is effective for improving adult height.
Tomohiro Ishii +8 more
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Growth hormone treatment for growth hormone deficient adults [PDF]
Journal of Clinical Pharmacy and Therapeutics, 1996 Growth hormone (GH) deficiency in adults is now recognized as a clinical syndrome with characteristic signs and symptoms. Numerous trials with daily subcutaneous biosynthetic human growth hormone (hGH) have been conducted in this patient group. Generally, improvements in insulin-like growth factor levels, decreases in total fat mass and increases in ...
W, Clark, M J, Kendall
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