Usefulness and Potential Pitfalls of Long-Acting Growth Hormone Analogs
Frontiers in Endocrinology, 2021 Daily recombinant human GH (rhGH) is currently approved for use in children and adults with GH deficiency (GHD) in many countries with relatively few side-effects.
Kevin C. J. Yuen +3 more
doaj +1 more source
Time for a general approval of growth hormone treatment in adults with Prader–Willi syndrome
Orphanet Journal of Rare Diseases, 2021 Prader-Willi syndrome (PWS) is a complex, multi-system, neurodevelopmental disorder characterised by neonatal muscular hypotonia, short stature, high risk of obesity, hypogonadism, intellectual disabilities, distinct behavioural/psychiatric problems and ...
Charlotte Höybye +3 more
doaj +1 more source
Effects of Thyroxine Exposure on Osteogenesis in Mouse Calvarial Pre-Osteoblasts [PDF]
, 2013 The incidence of craniosynostosis is one in every 1,800-2500 births. The gene-environment model proposes that if a genetic predisposition is coupled with environmental exposures, the effects can be multiplicative resulting in severely abnormal phenotypes.
A Mansukhani +58 more
core +6 more sources
Endocrinology Research and Practice, 2022 Ideas about hormone replacement therapy in hypopituitarism have changed since the discovery of increased atheroscferotic process caused by growth hormone (GH) deficiency.The aim of this study is to see the effect of GH therapy on cardiac functions and ...
Füsun Hamulu +5 more
doaj +2 more sources
The Involvement of the GH/IGF-I Axis in Cognitive Functions of Adult Patients and Healthy Subjects [PDF]
, 2012 From 1991, our research group and others have been investigating children with short stature who were born small for gestational age (SGA), both before and during treatment with biosynthetic growth hormone (GH).
Deijen, J.B., Drent, M.L., Driel, M.I.
core +7 more sources
A female survivor of childhood medulloblastoma presenting with growth-hormone-induced edema and inflammatory lesions: a case report [PDF]
, 2009 Introduction The improved survival of children with brain tumors has increased concerns about treatment-related sequelae. Growth hormone deficiency is frequently observed after craniospinal irradiation for medulloblastoma.
Veronica Biassoni +7 more
core +1 more source
Growth hormone during in vitro fertilization in older women modulates the density of receptors in granulosa cells, with improved pregnancy outcomes [PDF]
, 2018 OBJECTIVE To study the effect of aging and granulosa cell growth hormone receptor (GHR) expression, and the effect of growth hormone (GH) co-treatment during IVF on receptor expression. DESIGN Laboratory study.
Arfuso, Frank +4 more
core +1 more source
Initial Effect of Recombinant Human Growth Hormone Treatment in a Patient with Löwe Syndrome
Children, 2023 Objectives: Löwe syndrome (the oculocerebrorenal syndrome of Löwe, OCRL, OMIM #309000, ORPHA: 534) is a very rare multisystem X-linked disorder characterized by ocular, kidney and nervous system anomalies.
Violeta Iotova +5 more
doaj +1 more source
Role for growth regulation by estrogen in breast cancer 1 (GREB1) in hormone-dependent cancers [PDF]
, 2018 Sex hormones play important roles in the onset and progression of several cancers, such as breast, ovarian, and prostate cancer. Although drugs targeting sex hormone function are useful in treating cancer, tumors often develop resistance.
Cheng, Meng +2 more
core +2 more sources
Growth hormone state after completion of treatment with growth hormone. [PDF]
Archives of Disease in Childhood, 1987 After completion of treatment with growth hormone (GH) 19 patients with isolated 'idiopathic' GH deficiency and 15 with post-irradiation GH deficiency underwent retesting of GH secretion with an insulin tolerance test or an arginine stimulation test, or both. Patients with post-irradiation GH deficiency comprised 13 patients with central nervous system
Clayton, P. E. +2 more
openaire +2 more sources