Introduction Adult Growth hormone Deficiency is a well known phenomenon effecting both males and females. Adult Growth Hormone Deficiency is marked by a number of neuropsychiatric, cognitive performance, cardiac, metabolic, muscular, and bone symptoms ...
Madigan Margaret +9 more
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Growth hormone nadir during oral glucose load depends on waist circumference, gender and age: normative data in 231 healthy subjects. [PDF]
Objective (i) To analyse the predictors of GH suppression after standard glucose load (oGTT) in the healthy population and (ii) to establish the 97th percentile of GH nadir post-oGTT according to these variables.
AURIEMMA, RENATA SIMONA +7 more
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Adult growth hormone deficiency – benefits, side effects, and risks of growth hormone replacement
Deficiency of growth hormone (GH) in adults results in a syndrome characterized by decreased muscle mass and exercise capacity, increased visceral fat, impaired quality of life, unfavorable alterations in lipid profile and markers of cardiovascular risk,
Mary Lim Reed +2 more
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Growth hormone deficiency and the transition from pediatric to adult care
Objective: To discuss the approach to patients diagnosed with growth hormone deficiency (GHD) in childhood during the transition period from puberty to adulthood, focusing on the following: (1) physiology; (2) effects of recombinant human GH (rhGH ...
Ana Beatriz Winter Tavares +1 more
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Pituitary-adrenal axis in Prader Willi syndrome [PDF]
Purpose: Prader Willi syndrome (PWS) is a rare genetic condition that has concurrent endocrinological insufficiencies. The presence of growth hormone deficiency has been well documented, but adrenal insufficiency (AI) is not widely reported. A review was
Edgar, Olivia S. +2 more
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Estrone and estradiol concentrations in human ovaries, testes, and adrenals during the first two years of life [PDF]
To determine the origin of estrogens in infant blood, we measured estrone (E1) and estradiol (E2) in the gonads of 50 girls and 64 boys who died suddenly between birth and 2 yr of age as well as in the adrenals of 18 of these infant girls and 16 of the ...
Bidlingmaier, F. +4 more
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Effects of long-term growth hormone therapy in a girl with Floating-Harbor syndrome [PDF]
Floating-Harbor syndrome is a rare autosomal dominant disorder that presents with short stature, facial dysmorphism, significantly delayed bone age, skeletal abnormalities, speech and language problems, and intellectual disabilities.
Hyun Woo Son +4 more
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The visceral adiposity index is associated with insulin sensitivity and IGF-I levels in adults with growth hormone deficiency [PDF]
The visceral adiposity index, based on anthropometric and metabolic parameters, has been shown to be related to adipose tissue function and insulin sensitivity.
Ciresi, A. +3 more
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IGSF1 deficiency is a rare X-linked condition characterized by central hypothyroidism and a wide variety of other clinical features with variable prevalence, including a delayed pubertal testosterone rise and growth spurt in the context of normal or ...
Aslı Derya Kardelen +7 more
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Role of androgen and gonadotrophins in the development and function of the Sertoli cells and Leydig cells: data from mutant and genetically modified mice [PDF]
Development and maintenance of the male phenotype and establishment of fertility are all dependent upon the activity of the Sertoli cells and Leydig cells of the testis.
Abel, M.H. +4 more
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