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Adult growth hormone deficiency: current concepts. [PDF]
Neurol Med Chir (Tokyo), 2014 The clinical syndrome of adult growth hormone deficiency (AGHD) was widely recognized in the 1980s. In this review, we first describe the clinical features and diagnosis of AGHD and then state the effects of growth hormone (GH) therapy for these patients.
Fukuda I +3 more
europepmc +5 more sources
Diagnosing Growth Hormone Deficiency in Adults [PDF]
International Journal of Endocrinology, 2012 Adult growth hormone (GH) deficiency is a recognised syndrome associated with adverse phenotypic, metabolic, and quality-of-life features which improve in many patients when GH is substituted.
Nigel Glynn, Amar Agha
doaj +3 more sources
Corrigendum: Guidance for the treatment of adult growth hormone deficiency with somapacitan, a long-acting growth hormone preparation [PDF]
Frontiers in Endocrinology, 2023 Martin Bidlingmaier +6 more
doaj +2 more sources
Adult growth hormone deficiency [PDF]
Clinical Medicine, 2003 Growth hormone deficiency (GHD) in adults arises as a consequence of decreased secretion of somatotropin (GH) from the anterior pituitary. The diagnosis of GHD is dependent on the demonstration of a subnormal rise in serum GH in response to one or more dynamic stimulation tests in the presence of co-existing pituitary disease or other pituitary hormone
A M, Brooke, J P, Monson
openaire +2 more sources
Growth hormone treatment for growth hormone deficient adults [PDF]
Journal of Clinical Pharmacy and Therapeutics, 1996 Growth hormone (GH) deficiency in adults is now recognized as a clinical syndrome with characteristic signs and symptoms. Numerous trials with daily subcutaneous biosynthetic human growth hormone (hGH) have been conducted in this patient group. Generally, improvements in insulin-like growth factor levels, decreases in total fat mass and increases in ...
W, Clark, M J, Kendall
openaire +2 more sources
Archives of Endocrinology and Metabolism, 2022 SUMMARY We present the unique case of an adult Brazilian woman with severe short stature due to growth hormone deficiency with a heterozygous G to T substitution in the donor splice site of intron 3 of the growth hormone 1 (GH1) gene (c.291+1G>T).
Julia Haddad Labello +8 more
doaj +1 more source
Consensus guidelines for the diagnosis and treatment of adults with growth hormone deficiency: Summary statement of the growth hormone research society workshop on adult growth hormone deficiency [PDF]
, 1998 Based on the increasing body of evidence that adults with GH deficiency (somatotropin deficiency) have impaired health that improves with GH replacement, many countries have already approved the use of GH for replacement therapy in adults with GH ...
Clemmons, David +1 more
core +2 more sources
Growth hormone deficiency during young adulthood and the benefits of growth hormone replacement [PDF]
, 2016 Until quite recently, the management of children with growth hormone deficiency (GHD) had focussed on the use of recombinant human GH (rhGH) therapy to normalise final adult height.
Ahmed, S.F. +3 more
core +2 more sources
Endocrinology Research and Practice, 2022 Ideas about hormone replacement therapy in hypopituitarism have changed since the discovery of increased atheroscferotic process caused by growth hormone (GH) deficiency.The aim of this study is to see the effect of GH therapy on cardiac functions and ...
Füsun Hamulu +5 more
doaj +2 more sources
Adult growth hormone deficiency: academic extravagance or real clinical entity for the internist?
Italian Journal of Medicine, 2013 The Growth Hormone (GH) continues to act lifelong: it has been described, in fact, an Adult Growth Hormone Deficiency (AGHD) syndrome, involving several organs and functions, whose clinical aspects greatly improve with the administration of human ...
Giovanni Scanelli +3 more
doaj +1 more source