Results 81 to 90 of about 253,125 (355)

Discontinuation of long-term growth hormone treatment in adults with growth hormone deficiency: a survey of UK practice

Endocrine Connections
Objective: We conducted a survey of UK endocrine clinicians between June 2022 and August 2022 to understand current practices regarding GH treatment discontinuation in adults with growth hormone deficiency.
Sherwin Criseno, Helena Gleeson, Andrew A Toogood, Neil Gittoes, Anne Topping, Niki Karavitaki   +5 more
doaj   +1 more source

Phenotypic plasticity in a novel set of EGFR tyrosine kinase inhibitor‐adapted non‐small cell lung cancer cell lines

FEBS Open Bio, EarlyView.
Phenotypic plasticity in a newly established set of EGFR inhibitor‐adapted NSCLC cell lines during adaptation and in established cell lines. Here, we introduce novel sublines of the EGFR‐mutant non‐small cell lung cancer (NSCLC) cell lines HCC827 and HCC4006 adapted to the EGFR kinase inhibitors gefitinib (HCC827rGEFI2μm, HCC4006rGEFI1μm), erlotinib ...
Tharsagini V. Nanthaprakash, Campbell W. Gourlay, Ina Oehme, Michelle D. Garrett, Jindrich Cinatl Jr, Mark N. Wass, Martin Michaelis   +6 more
wiley   +1 more source

Diagnostic Criteria of Growth Hormone Deficiency Needs to be Reevaluated

Güncel Pediatri, 2012
ntroduction: In this study, we aimed to investigate the factors that determine response to growth hormone (GH) treatment in children with isolated idiopathic GH deficiency treated in our university hospital.
Enes Salı, Halil Sağlam, Ömer Tarım
doaj  

Safety of insulin tolerance test for the assessment of growth hormone deficiency in children [PDF]

, 2011
OBJECTIVE: To determine the safety of insulin tolerance test (ITT) for assessing growth hormone (GH) deficiency in children. METHODS: This hospital based study was conducted at the National Institute of Child Health, Karachi from 1st November 2008 till ...
Atta, Irum, Ibrahim, Mohsina Noor, Khan, Yasir Naqi, Lone, Saira Waqar, Qamar, Farah, Raza, Jamal   +5 more
core   +1 more source

Insulin-like growth factors and related proteins in plasma and cerebrospinal fluids of HIV-positive individuals. [PDF]

, 2015
BackgroundClinically significant dysregulation of the insulin-like growth factor (IGF) family proteins occurs in HIV-infected individuals, but the details including whether the deficiencies in IGFs contribute to CNS dysfunction are unknown.MethodsWe ...
Choi, Namjong, Lee, Sunhee C, Letendre, Scott, Lo, Yungtai, Suh, Hyeon-Sook   +4 more
core   +2 more sources

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

FEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu, Kanari Taki, Asuka Hayami, Komachi Kato, Yuka Nozaki, Yuhei Mizunoe, Takumi Narita, Ryoichi Mori, Yoshikazu Higami, Masaki Kobayashi   +9 more
wiley   +1 more source

Frequency of Growth Hormone Deficiency in Children with Short Stature

مجله دانشکده پزشکی اصفهان, 2010
Background: Growth hormone deficiency is an important and treatable cause for short stature in early diagnosed cases. This study was conducted to determine the frequency of growth hormone deficiency in children with short stature referred. Methods:
Shideh Assar, Hajieh Shahbazian, Kourosh Riahi, Keramat Kheradmand   +3 more
doaj  

Parameters Used for Evaluation of the Response to Treatment with Recombinant Human Growth Hormone in Paediatric and Adult Populations in Poland: Review

Journal of Education, Health and Sport
Introduction and purpose  Recombinant human growth hormone (rhGH) therapy has been the standard treatment  for paediatric short stature for many years, and a therapeutic option for the replacement therapy of growth hormone deficiency in the post ...
Agata Kotkowiak, Mikołaj Łabuda, Agnieszka Szema , Jakub Sikora, Karolina Knychalska, Klaudia Królikowska, Aleksandra Słojewska, Teresa Sowińska, Oliwia Mentel, Adrianna Bogucka   +9 more
doaj   +1 more source

Microphysiological Glomerular Filtration Barriers: Current Insights, Innovations, and Future Applications

Advanced Biology, EarlyView.
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran, Kieu Ngo, David Buob, Hanna Debiec, Pierre Ronco, Guillaume Perry   +5 more
wiley   +1 more source

Excessive growth hormone expression in male GH transgenic mice adversely alters bone architecture and mechanical strength [PDF]

, 2015
Patients with acromegaly have a higher prevalence of vertebral fractures despite normal bone mineral density (BMD), suggesting that GH overexpression has adverse effects on skeletal architecture and strength. We used giant bovine GH (bGH) transgenic mice
Chavassieux, P, Chenu, C, Hopkinson, M, Javaheri, B, Kopchick, J, Korbonits, M, Lim, SV, List, E, Marenzana, M, Pereira, M, Roux, J   +10 more
core   +1 more source