Results 21 to 30 of about 447,676 (302)
Journal of Medical Case Reports, 2021 Background Adjuvant endocrine therapy is recommended for the treatment of hormone-receptor-positive breast cancer. Aromatase inhibitors are associated with significant musculoskeletal adverse effects, likely through growth hormone/insulin-like growth ...
Sasan Mirfakhraee +3 more
doaj +1 more source
Counseling for Growth Hormone Therapy
Turkish Archives of Pediatrics, 2023 Growth hormone (GH) therapy is an integral part of the treatment of short stature. Over the period of the last few decades, due to the better availability of recombinant human growth hormone (rHGH), we have more clinical data on the uses of GH in various diseases.
Kalra, Sanjay +2 more
openaire +2 more sources
Growth Hormone Therapy in Adults with Prader-Willi Syndrome
Diseases, 2015 Prader-Willi syndrome (PWS) is characterized by hyperphagia, obesity if food intake is not strictly controlled, abnormal body composition with decreased lean body mass and increased fat mass, decreased basal metabolic rate, short stature, low muscle tone,
Karen S. Vogt, Jill E. Emerick
doaj +1 more source
Anabolic agents: Adjuncts to nutrition support [PDF]
, 2004 Anabolic agents as adjuncts to nutrition support therapy have been used to improve malnutrition and establish anabolism. Growth hormone, insulin-like growth factor, and anabolic steroids have been studied for their potential to reverse the catabolic ...
Gervasio, Jane M.
core +2 more sources
The role of IGF-1/GH in the aging process and the development of age-related diseases
Ожирение и метаболизм, 2023 One of the most important trends in geroscience is the search for the biomechanisms of aging and geroprotective methods. In recent years, more and more attention has been paid to the role of age-related decline in IGF-1 levels; processes that start with ...
A. K. Ilyushchenko +3 more
doaj +1 more source
Androgen receptor phosphorylation status at serine 578 predicts poor outcome in prostate cancer patients [PDF]
, 2016 Purpose: Prostate cancer growth is dependent upon androgen receptor (AR) activation, regulated via phosphorylation. Protein kinase C (PKC) is one kinase that can mediate AR phosphorylation. This study aimed to establish if AR phosphorylation by PKC is of
Edwards, J. +7 more
core +1 more source
Role for growth regulation by estrogen in breast cancer 1 (GREB1) in hormone-dependent cancers [PDF]
, 2018 Sex hormones play important roles in the onset and progression of several cancers, such as breast, ovarian, and prostate cancer. Although drugs targeting sex hormone function are useful in treating cancer, tumors often develop resistance.
Cheng, Meng +2 more
core +2 more sources
International Journal of Endocrinology, 2013 Objectives. Growth hormone deficiency patients exhibited reduced bone mineral density compared with healthy controls, but previous researches demonstrated uncertainty about the effect of growth hormone replacement therapy on bone in growth hormone ...
Peng Xue, Yan Wang, Jie Yang, Yukun Li
doaj +1 more source
Endocrine therapy for hormone receptor-positive metastatic breast cancer: American Society of Clinical Oncology Guideline [PDF]
, 2016 PURPOSE: To develop recommendations about endocrine therapy for women with hormone receptor (HR) -positive metastatic breast cancer (MBC). METHODS: The American Society of Clinical Oncology convened an Expert Panel to conduct a systematic review of ...
Barbara Fowble +19 more
core +1 more source
Neutrophil gelatinase-associated lipocalin (NGAL) predicts response to neoadjuvant chemotherapy and clinical outcome in primary human breast cancer [PDF]
, 2012 In our previous work we showed that NGAL, a protein involved in the regulation of proliferation and differentiation, is overexpressed in human breast cancer (BC) and predicts poor prognosis.
Arnold, Norbert +18 more
core +2 more sources