PATTERNS OF GROWTH INHIBITION [PDF]
Journal of Bacteriology, 1952 A M, MOORE, J B, BOYLEN
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Overcoming myelosuppression due to synthetic lethal toxicity for FLT3-targeted acute myeloid leukemia therapy. [PDF]
, 2014 Activating mutations in FLT3 confer poor prognosis for individuals with acute myeloid leukemia (AML). Clinically active investigational FLT3 inhibitors can achieve complete remissions but their utility has been hampered by acquired resistance and ...
He, Bai-Liang +9 more
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
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Evaluation of the Allelopathic Potential of Plant Extracts and its Comparison with Chemical Treatments on Galium aparine L. and Vicia villosa Roth. Weeds in Chickpea Fields [PDF]
پژوهشهای حفاظت گیاهان ایرانIntroductionWeeds represent a major constraint in agricultural production by competing with crops for essential resources such as light, water, nutrients, and space. In chickpea (Cicer arietinum) cultivation, species like Galium aparine L. (cleavers) and
Sadegh Jalilian +3 more
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Growth inhibition by vaccinia virus growth factor.
Journal of Biological Chemistry, 1990 Vaccinia virus growth factor (VGF), a highly glycosylated 77-residue epidermal growth factor (EGF)-like polypeptide encoded in vaccinia poxvirus, is reported to play an important role in stimulating growth of uninfected cells to facilitate virus infection.
Y Z, Lin, X H, Ke, J P, Tam
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Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
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Growth regulator inhibition of tobacco callus growth
Pesticide Biochemistry and Physiology, 1982 Abstract The activity of two groups of growth regulators, substituted dinitroanilines and nitrophenylhydrazines, were evaluated in a tobacco (Nicotiana tabacum L. “X-73”) callus tissue bioassay. Molar concentrations required to inhibit fresh weight gain by 50% (I50) was determined by using linear regression analysis on data obtained by testing a ...
Department of Plant Pathology and Physiology, Clemson University, Clemson, South Carolina 29631 USA ( host institution ) +4 more
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PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
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Supplemental Tables from Inhibition of <i>FoxM1</i>-Mediated DNA Repair by Imipramine Blue Suppresses Breast Cancer Growth and Metastasis [PDF]
, 2023 Subapriya Rajamanickam +12 more
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Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
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