Results 231 to 240 of about 9,724,101 (403)

The growth inhibition of yellow catfish (Pelteobagrus fulvidraco) under long-term low-concentration ammonia stress is regulated by the GH/IGF-1/IGFBP network

Changyi Sun, Ming Li, Shidong Wang, Yanjun Tang, Muzi Zhang, Haibo Jiang, Na Li, Chuanjie Qin   +7 more
openalex   +1 more source

Inhibition of angiogenesis and murine tumour growth by laminarin sulphate [PDF]

, 1996
Richard M. Hoffman, D. H. Paper, Jane Donaldson, H. Vogl   +3 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Targeted Hyaluronan Degradation Enhanced Tumor Growth Inhibition in Gastrointestinal Cancer Models. [PDF]

Cancers (Basel)
Zhou F, Mu G, Bi H, Chen L, Zha Z, Jin Y, Chiu ML.   +6 more
europepmc   +1 more source

Mechanisms of interferon-beta-induced inhibition ofToxoplasma gondiigrowth in murine macrophages and embryonic fibroblasts: role of immunity-related GTPase M1 [PDF]

, 2015
Motamed Elsayed Mahmoud, Fumiki Ui, Doaa Salman, Maki Nishimura, Yoshifumi Nishikawa   +4 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Evaluation of the Influence of Er:YAG Laser Parameters on the Effectiveness of Growth Inhibition of <i>Candida</i> Biofilms: An In Vitro Study. [PDF]

J Clin Med
Dembicka-Mączka D, Fiegler-Rudol J, Kępa M, Skaba D, Wiench R.   +4 more
europepmc   +1 more source

Dual Inhibition of RET and FGFR4 Restrains Medullary Thyroid Cancer Cell Growth [PDF]

, 2005
Shereen Ezzat, Ping Huang, Alan P.B. Dackiw, L. Sylvia   +3 more
openalex   +1 more source

Mechanisms and biological roles of contact-dependent growth inhibition systems.

Cold Spring Harbor Perspectives in Medicine, 2014
C. Hayes, Sanna Koskiniemi, Zachary C Ruhe, S. Poole, D. Low   +4 more
semanticscholar   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source