Results 31 to 40 of about 9,724,101 (403)

Biological Evaluation of Triorganotin Derivatives as Potential Anticancer Agents

open access: yesMolecules, 2023
Metal-derived platinum complexes are widely used to treat solid tumors. However, systemic toxicity and tumor resistance to these drugs encourage further research into similarly effective compounds.
Valeria Stefanizzi   +13 more
doaj   +1 more source

Medium alkalization due to carbon metabolism is largely responsible for inhibition of bacterial growth by Vibrio cholerae supernatants [PDF]

open access: yes, 2017
Vibrio cholerae is the causative agent of the diarrheal disease cholera. Many Vibrio species secrete antimicrobial factors, though the identity of such a factor has not been determined for any V. cholerae strain.
Becker, Miranda
core   +1 more source

TREMendous Macrophages Inhibit Hair Growth [PDF]

open access: yesCell Stem Cell, 2019
Tissue-resident immune cells with potent sensing and effector functions are well-placed to fundamentally aid tissue homeostasis via crosstalk with stem cells. In this issue of Cell Stem Cell, Wang et al. (2019) identify a dermis-resident TREM2+ macrophage subpopulation that promotes hair follicle stem cell quiescence via cytokine-mediated JAK-STAT ...
Tim, Dalessandri, Maria, Kasper
openaire   +2 more sources

Mitochondrial biogenesis and metabolic hyperactivation limits the application of MTT assay in the estimation of radiation induced growth inhibition

open access: yesScientific Reports, 2018
Metabolic viability based high throughput assays like MTT and MTS are widely used in assessing the cell viability. However, alteration in both mitochondrial content and metabolism can influence the metabolic viability of cells and radiation is a ...
Y. Rai   +8 more
semanticscholar   +1 more source

Overproduction of Laccase by Trametes versicolor and Pycnoporus sanguineus in Farnesol-Pineapple Waste Solid Fermentation

open access: yesFermentation, 2023
The effect of farnesol, a sesquiterpene alcohol, on the production of laccases by Trametes versicolor and Pycnoporus sanguineus in pineapple waste solid-state fermentation was evaluated.
Emanueli Backes   +7 more
doaj   +1 more source

Growth Hormone Inhibits Tumor Metastasis [PDF]

open access: yesCancer, 1991
The effect of growth hormone on tumor growth and metabolism in the tumor-bearing host is unknown. This study was done to determine the effect of recombinant growth hormone on primary tumor growth, tumor metastasis, and carcass weight in tumor-bearing animals. Twenty-seven female Lobund/Wistar rats with subcutaneous prostate tumor implants (PA-III) were
M H, Torosian, R B, Donoway
openaire   +2 more sources

BRC1 expression regulates bud activation potential but is not necessary or sufficient for bud growth inhibition in Arabidopsis

open access: yesDevelopment, 2017
The degree of shoot branching in Arabidopsis is determined by the activation of axillary buds. Bud activity is regulated by diverse environmental and developmental signals, often mediated via plant hormones, including auxin, strigolactone and cytokinin ...
M. Seale, Tom Bennett, O. Leyser
semanticscholar   +1 more source

Rapid and reversible root growth inhibition by TIR1 auxin signalling

open access: yesNature Plants, 2018
The phytohormone auxin is the information carrier in a plethora of developmental and physiological processes in plants1. It has been firmly established that canonical, nuclear auxin signalling acts through regulation of gene transcription2.
M. Fendrych   +8 more
semanticscholar   +1 more source

ANTI-TUMOR EFFECTS OF SIMVASTATIN ON UMR-106 OSTEOSARCOMA CELL LINE

open access: yesRevista de la Academia Colombiana de Ciencias Exactas, Físicas y Naturales, 2023
Statins have been widely used for the treatment of hypercholesterolemia and other cardiovascular diseases. Recently, statins have been studied for their apoptotic effects, making them relevant for cancer prevention and treatment; however, their exact ...
María Claudia Sandoval-Usme   +4 more
doaj   +1 more source

Targeted BCL2 inhibition effectively inhibits neuroblastoma tumour growth [PDF]

open access: yesEuropean Journal of Cancer, 2012
Genomic aberrations of key regulators of the apoptotic pathway have hardly been identified in neuroblastoma. We detected high BCL2 mRNA and protein levels in the majority of neuroblastoma tumours by Affymetrix expression profiling and Tissue Micro Array analysis.
Lamers, Fieke   +9 more
openaire   +2 more sources

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