Results 51 to 60 of about 9,488,957 (383)
Mechanisms of glucocorticoid inhibition of growth
Kidney International, 1978 Mechanisms whereby glucocorticoids might inhibit growth are reviewed from the perspective of glucocorticoid effects on cell metabolism and growth. Although glucocorticoids given to patients decrease levels of growth hormone and possible somatomedins, the effect of glucocorticoids on growth is not reversed when growth hormone is given.
openaire +3 more sources
AKT activation controls cell survival in response to HDAC6 inhibition. [PDF]
, 2016 HDAC6 is emerging as an important therapeutic target for cancer. We investigated mechanisms responsible for survival of tumor cells treated with a HDAC6 inhibitor.
Aboagye, EO +3 more
core +1 more source
PCC0208057 as a small molecule inhibitor of TRPC6 in the treatment of prostate cancer
Frontiers in PharmacologyProstate cancer (PCa) is a common malignant tumor, whose morbidity and mortality keep the top three in the male-related tumors in developed countries.
Yingjie Wei +8 more
doaj +1 more source
Plants, 2016 Plant growth is often constrained by the limited availability of resources in the microenvironment. Despite the continuous threat of attack from insect herbivores and pathogens, investment in defense represents a lost opportunity to expand photosynthetic
Nathan E. Havko +5 more
doaj +1 more source
Biological Evaluation of Triorganotin Derivatives as Potential Anticancer Agents
Molecules, 2023 Metal-derived platinum complexes are widely used to treat solid tumors. However, systemic toxicity and tumor resistance to these drugs encourage further research into similarly effective compounds.
Valeria Stefanizzi +13 more
doaj +1 more source
Growth Inhibition of Medically Antibiotic Resistant Bacteria by Sponge-associated Bacteria [PDF]
, 2008 The improper and uncontrolled uses of antibiotics against pathogenic bacteria have resulted in theoccurrence of Multi Drugs Resistant bacteria. There is now an urgency to find alternative antibioticsto combat these bacteria.
Radjasa, O. K. (Ocky)
core
Acetate Metabolism and the Inhibition of Bacterial Growth by Acetate
Journal of Bacteriology, 2019 High concentrations of organic acids such as acetate inhibit growth of Escherichia coli and other bacteria. This phenomenon is of interest for understanding bacterial physiology but is also of practical relevance.
Stéphane Pinhal +3 more
semanticscholar +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Frontiers in Plant ScienceThe phenology has gained considerably more attention in recent times of climate change. The transition from vegetative to reproductive phases is a critical process in the life history of plants, closely tied to phenology.
Si-Hyun Park, Jae Geun Kim, Jae Geun Kim
doaj +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source