Results 51 to 60 of about 9,724,101 (403)

Perfluorocarbon nanoparticles enhance reactive oxygen levels and tumour growth inhibition in photodynamic therapy

Nature Communications, 2015
Photodynamic therapy (PDT) kills cancer cells by converting tumour oxygen into reactive singlet oxygen (1O2) using a photosensitizer. However, pre-existing hypoxia in tumours and oxygen consumption during PDT can result in an inadequate oxygen supply ...
Yuhao Cheng, Hao Cheng, Chenxiao Jiang, X. Qiu, Kaikai Wang, Wei Huan, A. Yuan, Jinhui Wu, Yiqiao Hu   +8 more
semanticscholar   +1 more source

Histone acetyltransferase inhibitor CPTH6 preferentially targets lung cancer stem-like cells [PDF]

, 2016
Cancer stem cells (CSCs) play an important role in tumor initiation, progression, therapeutic failure and tumor relapse. In this study, we evaluated the efficacy of the thiazole derivative 3-methylcyclopentylidene-[4-(4’-chlorophenyl)thiazol-2-yl ...
Buglioni, Simonetta, Carradori, Simone, DE LUCA, Teresa, De Maria, Ruggero, Del Bufalo, Donatella, Desideri, Marianna, DI MARTILE, Marta, Eramo, Adriana, Gabellini, Chiara, Mai, Antonello, Milella, MICHELE STANISLAW, Rotili, Dante, Secci, Daniela, Sette, Giovanni, Trisciuoglio, Daniela   +14 more
core   +4 more sources

Peroxoniobium inhibits leukemia cell growth

RSC Advances, 2018
A new class of polyoxoniobate complex has been synthesized and characterized as a novel anticancer agent for photodynamic therapy.
Elene C. Pereira-Maia, Ivina P. Souza, Kelen J. R. C. Nunes, Alexandre A. Castro, Teodorico C. Ramalho, Fernando Steffler, Helio A. Duarte, Ana Pacheli, Poliana Chagas, Luiz C. A. Oliveira   +9 more
openaire   +4 more sources

Deficiency of G1 regulators P53, P21Cip1 and/or pRb decreases hepatocyte sensitivity to TGFbeta cell cycle arrest [PDF]

, 2015
TGFbeta is critical to control hepatocyte proliferation by inducing G1-growth arrest through multiple pathways leading to inhibition of E2F transcription activity.
Bellamy, Christopher O, Dunbar, Donald R, Harrison, David J, Prost, Sandrine, Sheahan, Sharon   +4 more
core   +1 more source

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control.

Genes & Development, 2007
The Hippo pathway plays a key role in organ size control by regulating cell proliferation and apoptosis in Drosophila. Although recent genetic studies have shown that the Hippo pathway is regulated by the NF2 and Fat tumor suppressors, the physiological ...
Bin Zhao, Xiaomu Wei, Weiquan Li, Ryan S. Udan, Qian Yang, Joungmok Kim, Joe X. Xie, T. Ikenoue, Jindan Yu, Li Li, Pan Zheng, K. Ye, A. Chinnaiyan, G. Halder, Z. Lai, K. Guan   +15 more
semanticscholar   +1 more source

Comparative Growth Inhibition of Bread Spoilage Fungi by Different Preservative Concentrations Using a Rapid Turbidimetric Assay System

Frontiers in Microbiology, 2021
Bread and intermediate moisture bakery products are mainly spoiled by yeasts and filamentous fungi. The inoculum load and preservation system used determines their shelf life.
Marcelo Valle Garcia, Esther Garcia-Cela, Esther Garcia-Cela, Naresh Magan, Marina Venturini Copetti, Angel Medina   +5 more
doaj   +1 more source

Frondoside A suppressive effects on lung cancer survival, tumor growth, angiogenesis, invasion, and metastasis [PDF]

, 2013
A major challenge for oncologists and pharmacologists is to develop less toxic drugs that will improve the survival of lung cancer patients. Frondoside A is a triterpenoid glycoside isolated from the sea cucumber, Cucumaria frondosa and was shown to be a
Adrian, Thomas E, Al Sultan, Mahmood Ahmed, Arafat, Kholoud, Attoub, Samir, Bracke, Marc, Collin, Peter, De Wever, Olivier, Gelaude, An, Takahashi, Takashi   +8 more
core   +3 more sources

Local Transcriptional Control of YUCCA Regulates Auxin Promoted Root-Growth Inhibition in Response to Aluminium Stress in Arabidopsis

PLoS Genetics, 2016
Auxin is necessary for the inhibition of root growth induced by aluminium (Al) stress, however the molecular mechanism controlling this is largely unknown.
Guangchao Liu, Shan Gao, Huiyu Tian, Wenwen Wu, H. Robert, Zhaojun Ding   +5 more
semanticscholar   +1 more source

The Effects of Mentha × piperita Essential Oil on C. albicans Growth, Transition, Biofilm Formation, and the Expression of Secreted Aspartyl Proteinases Genes

Antibiotics, 2019
The rise in resistance and changes in the spectrum of Candida infections have generated enormous interest in developing new antifungal drugs using natural molecules such as plant essential oils (EOs).
Chahrazed Benzaid, Amine Belmadani, Ryad Djeribi, Mahmoud Rouabhia   +3 more
doaj   +1 more source

Interactions of asbestos-activated macrophages with an experimental fibrosarcoma [PDF]

, 1983
Supernatants from in vivo asbestos-activated macrophages failed to show any cytostatic activity against a syngeneic fibrosarcoma cell line in vitro. UICC chrysotile-induced peritoneal exudate cells also failed to demonstrate any growth inhibitory effect ...
A Ewing, Ames B. N., Cohn Z. A., Davies P., Gabizon A., J M Davis, K Donaldson, K James, Keller R, Lowry 0., Pylev L. N., Raz A., Topping D. C.   +12 more
core   +2 more sources