Results 71 to 80 of about 9,488,957 (383)
Ligation of anti-cancer drugs to self-assembling ultrashort peptides by click chemistry for localized therapy [PDF]
, 2013 Self-assembling ultrashort peptides from aliphatic amino acids were functionalized with platinum anti-cancer drugs by click chemistry. Oxaliplatin-derived hybrid peptide hydrogels with up to 40% drug loading were tested for localized breast cancer ...
Chan, Kiat-Hwa +8 more
core +1 more source
Growth rate inhibition metrics correct for confounders in measuring sensitivity to cancer drugs
Nature Methods, 2016 Drug sensitivity and resistance are conventionally quantified by IC50 or Emax values, but these metrics are highly sensitive to the number of divisions taking place over the course of a response assay.
M. Hafner +3 more
semanticscholar +1 more source
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Inhibition of Growth of Streptococci by Adenine.
Experimental Biology and Medicine, 1961 SummaryAdenine, at a concentration of 5 μg/ml or above in a synthetic medium, has been shown to inhibit growth of 2 strains of S. pyogenes, S23 and C203U. The inhibition can be overcome by addition of xanthine, guanine or hypoxanthine at approximately one-third the molar concentration of the inhibitor.
Jimmie R. Nelson, Alan G. C. White
openaire +3 more sources
Investigation to identify paint coatings resistive to microorganism growth [PDF]
, 1971 All selected coatings contain nutrients that support microbial growth and survival. Incorporation of microbiocidal agents into coatings more susceptible to attack is recommended for improved inhibition of microorganism growth and for increased protection
Cooper, C. W., Kemp, H. T.
core +1 more source
Axon growth inhibition by RhoA/ROCK in the central nervous system
Frontiers in Neuroscience, 2014 Rho kinase (ROCK) is a serine/threonine kinase and a downstream target of the small GTPase Rho. The RhoA/ROCK pathway is associated with various neuronal functions such as migration, dendrite development, and axonal extension.
Y. Fujita, T. Yamashita
semanticscholar +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Planta Daninha, 1991 Com o objetivo de estudar o efeito de diferentes doses de metribuzin na taxa fotossintética líquida e na tolerância de plantas de soja (Glycine max (L.) Merill, 'Uberaba' e 'Alvorada '), foi conduzido um experimento, em casa de vegetação, no Centro de ...
P. J. Silva Neto +3 more
doaj +1 more source
Environment Conservation Journal, 2023 The present investigation aimed to determine the per cent growth inhibition of different fungicides against Alternaria burnsii, the causal agent of cumin blight. The study was conducted during 2020-21 at the Experiential Unit of Plant Pathology, College
Sunaina Varma, Data Ram Kumhar
doaj +1 more source
GLUT1 inhibition blocks growth of RB1-positive triple negative breast cancer
Nature Communications, 2019 Triple negative breast cancer (TNBC) is a deadly form of breast cancer due to the development of resistance to chemotherapy affecting over 30% of patients. New therapeutics and companion biomarkers are urgently needed. Recognizing the elevated expression
Qin Wu +22 more
semanticscholar +1 more source