Results 161 to 170 of about 1,482,290 (356)

Psi promotes Drosophila wing growth via direct transcriptional activation of cell cycle targets and repression of growth inhibitors.

Development, 2023
Zaytseva O, Mitchell NC, Muckle D, Delandre C, Nie Z, Werner JK, Lis JT, Eyras E, Hannan RD, Levens DL, Marshall OJ, Quinn LM.   +11 more
europepmc   +1 more source

Transforming growth factor beta 1 directly and reversibly inhibits the initial cell divisions of long-term repopulating hematopoietic stem cells [PDF]

, 1996
Ewa Sitnicka, FW Ruscetti, GV Priestley, NS Wolf, SH Bartelmez   +4 more
openalex   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Machine Learning Platform to Discover Novel Growth Inhibitors of Neisseria gonorrhoeae. [PDF]

Pharm Res, 2020
Pereira JC, Daher SS, Zorn KM, Sherwood M, Russo R, Perryman AL, Wang X, Freundlich MJ, Ekins S, Freundlich JS.   +9 more
europepmc   +1 more source

Hsp90 inhibitor celastrol reinstates growth plate angiogenesis in thiram-induced tibial dyschondroplasia [PDF]

, 2016
Fazul Nabi, Muhammad Shahzad, Jingying Liu, Kun Li, Zhaoqing Han, Ding Zhang, Mujahid Iqbal, Jiakui Li   +7 more
openalex   +1 more source

Additional file 3 of A plant-based medicinal food inhibits the growth of human gastric carcinoma by reversing epithelial–mesenchymal transition via the canonical Wnt/β-catenin signaling pathway

, 2021
Xuxi Chen, Wuyang Yue, Lin Tian, Na Li, Yiyi Chen, Lishi Zhang, Jinyao Chen   +6 more
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Epidermal Growth Factor Inhibitor-induced Cutaneous Toxicity Improves with Moisturizers

, 2020
Ichiko Morino, Aika Okuno, Yuka Hirakawa, Yumiko Saya, Yumi Murakami, Fukumi Furukawa, Hiroshi Matsunaka   +6 more
openalex   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Derivatives of 1,2,4-triazole imines acting as dual iNOS and tumor cell growth inhibitors. [PDF]

Bioorg Chem, 2020
Guillon C, Vetrano AM, Saxena J, Hunter A, Verderone G, Finetti TM, Wisnoski J, DeMatteo PW, Rapp RD, Heindel ND, Joseph LB, Heck DE, Laskin JD.   +12 more
europepmc   +1 more source