Results 251 to 260 of about 1,482,290 (356)

Data Sheet 2_Artemisia absinthium L. ethanol extract inhibits the growth of gastrointestinal cancer cells by inducing apoptosis and mitochondria-dependent pathway.xlsx

Ting Li (117885), Shaoqi Yu (7489247), Zihang Ma (16409619), Jinyao Li (4392487), Lijie Xia (366194), Yan Feng (128912)   +5 more
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Weed Suppressing Potential and Isolation of Potent Plant Growth Inhibitors from Castanea crenata Sieb. et Zucc. [PDF]

Molecules, 2018
Tuyen PT, Xuan TD, Tu Anh TT, Mai Van T, Ahmad A, Elzaawely AA, Khanh TD.   +6 more
europepmc   +1 more source

Image 1_Targeting USP42 induces DNA damage and inhibits cell growth in prostate cancer.pdf

Yinghao Zhou (10106450), Chenchen Chen (17915971), Yibo Meng (17915968), Jianchao Ge (9751856), Shengkui Meng (21699020), Xillong Wang (21699023), Yaozong Xu (17811268), Guowei Shi (1685962), Wandong Yu (10106444), Xuetao Hu (6735044), Jun Zhang (48506)   +10 more
openalex   +1 more source

Lentivirus-mediated shRNA interference targeting vascular endothelial growth factor inhibits angiogenesis and progression of human pancreatic carcinoma

, 2012
Xin Zhao, Dongming Zhu, Wen-Juan Gan, Zhi Li, Jianglei Zhang, Hua Zhao, Jin Zhou, Dechun Li   +7 more
openalex   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Image 2_The RET inhibitor pralsetinib suppresses TMZ-resistant glioma growth by regulating spermine production.tif

Lingyun Ma (527380), Hang Gong (4258147), Wei Sun (93580), Jialing Deng (17174362), Qinghua Zhang (145923), Jianzhao Niu (5936966), Huimin Sun (3121266), Xue Han (25073), Tingting Du (9414), Nina Xue (554993), Ming Ji (504536), Qian Liu (135614)   +11 more
openalex   +1 more source

Glucocorticoid inhibits thrombin-induced expression of platelet-derived growth factor A-chain and heparin-binding epidermal growth factor-like growth factor in human aortic smooth muscle cells.

, 1993
Toru Nakano, Elaine W. Raines, Judith A. Abraham, Fine Wenzel, Shigeki Higashiyama, Michael Klagsbrun, R. Ross   +6 more
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Efficacy and Mechanisms of CDK4/6 Inhibitors in Breast Cancer: Advancing Targeted Therapeutic Strategies. [PDF]

Oncol Res
Patwekar M, Patwekar F, Kari ZA, Zain MRAM, Mohammed A, Sharma R.   +5 more
europepmc   +1 more source