Results 301 to 310 of about 1,482,290 (356)
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Pentapeptide Growth Inhibitors
1990The hemoregulatory peptide and the epidermal pentapeptide are small oligopeptides (molecular weight around 500–600) involved in the regulation of proliferation in their respective tissues in vitro and in vivo. The identification of these peptides was achieved after a 20–year-long search for specific endogenous feedback inhibitors of proliferation ...
W. R. Paukovits, K. Elgjo, O. D. Laerum
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Fibroblast Growth Factors and Their Inhibitors
Current Pharmaceutical Design, 2000Fibroblast growth factors (FGFs) are members of a family of polypeptides synthesized by a variety of cell types during the processes of embryonic development and in adult tissues. FGFs have been detected in normal and malignant cells and show a biological profile that includes mitogenic and angiogenic activity with a consequent crucial role in cell ...
MANETTI, FABRIZIO +2 more
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Mammary-Derived Growth Inhibitor (MDGI)
1991In contrast to the steadily increasing number of growth factors capable of stimulating cells to synthesize DNA and to divide, very little is known about their potential antagonists, which are supposed to contribute to balanced growth and development by inhibiting cellular proliferation.
R, Grosse +6 more
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Inhibitors of growth factor signalling
Endocrine-Related Cancer, 2005The therapeutic utility of trastuzumab (‘Herceptin’) in breast cancer patients with tumours that overexpress erbB2 established the principle that targeted inhibition of specific signal transduction pathways can provide a new approach to cancer treatment.
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Growth, Metabolism, and Growth Inhibitors of Mesenchymal Stem Cells
Tissue Engineering Part A, 2009Most therapeutic applications of bone marrow stromal cells (MSCs), or mesenchymal stem cells, require expansion of these cells. This study aimed to obtain more information about human MSCs regarding their expansion characteristics: growth, metabolism, and growth inhibitors.
Schop, D. +6 more
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Straight-Growth Inhibitors in Glucose
Nature, 1958SEVERAL authors1–5, when partitioning crude ether extracts of plant material, have saturated the aqueous phase with glucose to facilitate its separation from the ether phase.
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1977
Our interest in this subject arose from the discovery (43) of the selective herbicides, 3,5-diiodo-4-hydroxybenzonitrile (ioxynil) and the dibromo derivative (bromoxynil), both of which are widely used in agriculture. This discovery stimulated research on their mode of action and metabolism, and investigations on chemical structure in relation to ...
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Our interest in this subject arose from the discovery (43) of the selective herbicides, 3,5-diiodo-4-hydroxybenzonitrile (ioxynil) and the dibromo derivative (bromoxynil), both of which are widely used in agriculture. This discovery stimulated research on their mode of action and metabolism, and investigations on chemical structure in relation to ...
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Growth Factors and Growth Factor Inhibitors
1997This chapter will outline novel treatment strategies predicated on the modulation of growth factor or cytokine-mediated signal transduction pathways. Several excellent recent monographs have addressed this tissue from the point of view of inhibitors of individual pathway constituents (1,2).The current focus will be on defining the pathways potentially ...
Edward A. Sausville, Dan L. Longo
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Cinnamylphenols as inhibitors of fungal growth
Canadian Journal of Microbiology, 1972Cinnamylpyrogallol was found to be a greater inhibitor of fungal growth than either cinnamyl alcohol or pyrogallol. Antifungal activity decreased with time owing to oxidation of the compound in solution. Cinnamylphloroglucinol was less active than cinnamylpyrogallol against the 27 species of fungi (including dermatophytes) tested.
G, Dupuis +3 more
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Dichloropyrimidines: Specific inhibitors of virus growth
Experientia, 1977Dichloropyrimidines can be considered as a new group of antiviral substances having a common spectrum of inhibitory action.
O, Flore +5 more
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