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Mammary-Derived Growth Inhibitor
1990Today search for growth-regulating polypeptides is guided by a model which postulates control of cell proliferation by both positive and negative signals. Although Bullough and Lawrence (1960) and Iversen (1960) developed the chalone theory in 1960, the existence of growth inhibitors was not demonstrated until recently.
R. Grosse, P. Langen
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Control of Liver Growth by Growth Inhibitors (Chalones)
1979Chalones are auto-inhibitory factors which control tissue growth by reducing cell multiplication. To belong to this class of factors, a product extracted from blood or organs has to meet the following conditions: (1) It acts specifically on one type of cells, (2) the same cells produce the factor and are sensitive to it, and (3) the factor is truly ...
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Myelin-associated inhibitors of neurite growth
Experimental Neurology, 1990CNS myelin and oligondendrocyte membranes contain two minor proteins with strong inhibitory effects on growing neurites (neurite growth inhibitors NI-35 and NI-250). Monoclonal antibodies (IN-1, IN-2) were obtained that neutralize this activity in a variety of culture assays including adult rat optic nerve explants, which are invaded by growing ...
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1998
The Growth-Inhibitory Effects of TGFB The Retinoblastoma Family and Growth Control The Growth Regulatory Role of p21(WAF1/GIP1) Mechanisms of Cell Cycle Blocks at the G2/M Transition Mechanisms of Interferon Action Growth-Inhibiting N-Substituted Endogenous Peptides Endogenous Angiogenesis Inhibitors: Angiostatin, Endostatin, and Other Proteolytic ...
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The Growth-Inhibitory Effects of TGFB The Retinoblastoma Family and Growth Control The Growth Regulatory Role of p21(WAF1/GIP1) Mechanisms of Cell Cycle Blocks at the G2/M Transition Mechanisms of Interferon Action Growth-Inhibiting N-Substituted Endogenous Peptides Endogenous Angiogenesis Inhibitors: Angiostatin, Endostatin, and Other Proteolytic ...
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[Epidermal growth factor inhibitors].
La Revue de medecine interne, 2003Tyrosine kinases are implicated in the normal cellular proliferation and in malignant transformation. Among the tyrosine kinase receptors, one of best described is the Epidermal Growth Factor Receptor (EGFR), which is widely expressed in particular in epithelial cells and in many human carcinomas.Compounds have been developed that target either the ...
C, Delbaldo, S, Faivre, E, Raymond
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Growth Inhibitor of Hamster Fibroblast Cells
Nature, 1966THE hamster fibroblast cell line BHK21/13 (ref. 1) has been used extensively in investigations of transformation by polyoma virus2. This report describes a difference in a possible aspect of the regulation of growth in BHK21/13 and a polyoma-transformed derivative, PyY (ref. 3).
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Inositol a Tumor Growth Inhibitor
Science, 1943D, Laszlo, C, Leuchtenberger
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